I A Davis
Overview
Explore the profile of I A Davis including associated specialties, affiliations and a list of published articles.
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13
Citations
169
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Recent Articles
1.
Kumaraguru U, Davis I, Deshpande S, Tevethia S, Rouse B
J Immunol
. 2001 Jan;
166(2):1066-74.
PMID: 11145686
Recent observations have indicated that viral persistence and tumor spreading could occur because of effector function-defective CD8(+) T cells. Although chronic exposure to Ag, lack of CD4 help, and epitope...
2.
Kennel S, Chappell L, Dadachova K, Brechbiel M, Lankford T, Davis I, et al.
Cancer Biother Radiopharm
. 2000 Aug;
15(3):235-44.
PMID: 10941530
Several alpha particle emitting radioisotopes have been studied for use in radioimmunotherapy. Ac-225 has the potential advantages of a relatively long half life of 10 days, and a yield of...
3.
Kennel S, Lankford T, Foote L, Davis I, Boll R, Mirzadeh S
Cancer Biother Radiopharm
. 2000 Jun;
14(5):371-9.
PMID: 10850322
Rat MAb 201B, which binds to murine thrombomodulin, can deliver up to 50% of the injected dose of attached radioisotopes to the lung vascular endothelium. We have shown previously that...
4.
Kennel S, Davis I, Branning J, Pan H, Kabalka G, Paulus M
Med Phys
. 2000 Jun;
27(5):1101-7.
PMID: 10841415
A model lung tumor system has been developed in mice for the evaluation of vascular targeted radioimmunotherapy. In this model, EMT-6 mammary carcinoma tumors growing in the lung are treated...
5.
Davis I, Rouse B
Lab Anim
. 2000 Apr;
34(1):111-4.
PMID: 10759375
The transmigration of lymphocytes across vascular endothelium is a critical step for the localization of lymphocytes to lymph nodes in both naive and immune reactive states. Mice deficient in lymphotoxin-alpha...
6.
Davis I, Kennel S
Clin Cancer Res
. 1999 Nov;
5(10 Suppl):3160s-3164s.
PMID: 10541358
A monoclonal antibody (201B) specific to murine thrombomodulin, covalently linked to cyclohexyl diethylenetriaminepentaacetic acid, successfully delivers chelated 213Bi, an alpha-particle emitter, (213Bi-201B) rapidly to lung vascular endothelium. When injected at...
7.
Davis I, Glowienka K, Boll R, Deal K, Brechbiel M, Stabin M, et al.
Nucl Med Biol
. 1999 Sep;
26(5):581-9.
PMID: 10473198
The biodistribution and tissue toxicity of intravenously administered 225-actinium (225Ac) complexed with acetate, ethylene diamine tetraacetic acid (EDTA), 1, 4, 7, 10, 13-pentaazacyclopentadecane-N, N', N", N"', N""-pentaacetic acid (PEPA), or...
8.
Deal K, Davis I, Mirzadeh S, Kennel S, Brechbiel M
J Med Chem
. 1999 Jul;
42(15):2988-92.
PMID: 10425108
The favorable nuclear properties of actinium-225 ((225)Ac) have led to proposal of this isotope for use in radioimmunotherapy. In an effort to reduce the toxicity of free (225)Ac, a series...
9.
Kennel S, Lankford P, Foote L, Davis I
Hybridoma
. 1999 Jan;
17(6):509-15.
PMID: 9890706
From mice immunized with rat endothelial cell membranes, we isolated several hybridomas secreting monoclonal antibodies (MAbs) to a 45-kDa glycoprotein expressed on the surface of cultured cells. One of these...
10.
Davis I, Rouse B
Cell Immunol
. 1998 Oct;
189(2):116-24.
PMID: 9790725
The effects of lymphotoxin-alpha (LT-alpha) deficiency on mucosal immune status has not been defined. We utilized severe combined immunodeficiency (scid) mice as recipients of both mutant and wild-type whole splenocytes...