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B T Rouse

Explore the profile of B T Rouse including associated specialties, affiliations and a list of published articles. Areas
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Articles 259
Citations 4108
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Recent Articles
1.
Banks T, Hariharan M, Rouse B
Methods Mol Med . 2011 Mar; 10:327-43. PMID: 21374239
Protective immunity against a eajority of viral infections is mediated by a combination of both humoral and cell-mediated immune responses. However, in the case of herpesvirus infections, where viral spread...
2.
Rouse B
J Intern Med . 2007 Jun; 262(1):78-95. PMID: 17598816
The healthy host does not normally develop tissue destructive autoimmunity in part because of the presence of natural regulatory T cells. These cells are best identified by their expression of...
3.
Kumaraguru U, Rouse B
Expert Opin Investig Drugs . 2005 Jul; 7(2):219-24. PMID: 15991953
There is currently no acceptable vaccine available for the control of herpes simplex virus (HSV) infection. This review discusses the reasons for the past failures and evaluates the prospect that...
4.
Kumaraguru U, Rouse B
J Leukoc Biol . 2002 Sep; 72(3):564-70. PMID: 12223525
Herpes simplex virus (HSV) infection results in rapid and sustained up-regulation of interleukin (IL)-12, but the primary cellular source of IL-12 after HSV infection is unknown. We demonstrate that this...
5.
Rouse B, Gierynska M
Herpes . 2002 Feb; 8 Suppl 1:2A-5A. PMID: 11867027
This article discusses some possible reasons why people vary in susceptibility to primary infection by herpes simplex virus (HSV), and, in addition, why some individuals suffer lesions upon viral reactivation...
6.
Eo S, Pack C, Kumaraguru U, Rouse B
Expert Opin Biol Ther . 2001 Dec; 1(2):213-25. PMID: 11727531
Herpes simplex virus (HSV) lacks an effective vaccine. Despite its prevalence and importance HSV infection is not controlled with an acceptable vaccine. Perhaps the best candidate and so far untested...
7.
Eo S, Kumaraguru U, Rouse B
J Immunol . 2001 Sep; 167(7):3592-9. PMID: 11564771
Lymphotoxin alpha-deficient (LTalpha-/-) mice, which lack lymph nodes and possess a disorganized spleen, develop dysfunctional CD8+ T cells upon HSV infection and readily succumb to herpes encephalitis. Such mice do...
8.
Zheng M, Deshpande S, Lee S, Ferrara N, Rouse B
J Virol . 2001 Sep; 75(20):9828-35. PMID: 11559816
This report analyzes the role of vascular endothelial growth factor (VEGF)-induced angiogenesis in the immunoinflammatory lesion stromal keratitis induced by ocular infection with herpes simplex virus (HSV). Our results show...
9.
Zheng M, Schwarz M, Lee S, Kumaraguru U, Rouse B
Am J Pathol . 2001 Sep; 159(3):1021-9. PMID: 11549594
Stromal keratitis resulting from ocular infection with herpes simplex virus is a common cause of blindness. This report investigates the role of neovascularization in the pathogenesis of stromal keratitis by...
10.
Eo S, Lee S, Kumaraguru U, Rouse B
Vaccine . 2001 Sep; 19(32):4685-93. PMID: 11535317
The CCR7 ligands, secondary lymphoid tissue chemokine (SLC) and Epstein-Barr virus-induced molecule 1 ligand chemokine (ELC), were recently recognized as key molecules in establishing functional microenvironments for the initiation of...