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Hyeung-Rak Kim

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Articles 49
Citations 716
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Recent Articles
1.
Joung E, Lee M, Lee M, Gwon M, Shin T, Ryu H, et al.
Planta Med . 2023 Oct; 90(1):25-37. PMID: 37848042
This study aims to explore the anti-inflammatory mechanisms of sargachromenol in both RAW 264.7 cells and lipopolysaccharide (LPS)-treated mice, as previous reports have suggested that sargachromenol possesses anti-aging, anti-inflammatory, antioxidant,...
2.
Joung E, Cao L, Gwon W, Kwon M, Lim K, Kim H
Foods . 2022 Feb; 11(3). PMID: 35159480
Colitis is a colon mucosal disorder characterized by intestinal damage and inflammation. This current study aimed to evaluate the effect of meroterpenoid-rich ethanoic extract of a brown algae, (MES) on...
3.
Kim D, Lee Y, Kim H, Park Y, Hwang H, Rhim H, et al.
Sci Rep . 2021 Oct; 11(1):21315. PMID: 34716371
Sargassum serratifolium (C. Agardh) C.Agardh, a marine brown alga, has been consumed as a food and traditional medicine in Asia. A previous study showed that the meroterpenoid-rich fraction of an...
4.
Azam M, Kim J, Choi C, Choi J, Lee B, Kim H
Foods . 2021 Oct; 10(10). PMID: 34681303
Hyperpigmentation diseases of the skin require topical treatment with depigmenting agents. We investigated the hypopigmented mechanisms of sargahydroquinoic acid (SHQA) in alpha-melanocyte-stimulating hormone (α-MSH)-stimulated B16F10 cells. SHQA reduced cellular tyrosinase...
5.
Moon K, Lee M, Hwang T, Choi C, Kim M, Kim H, et al.
Redox Biol . 2021 Aug; 46:102101. PMID: 34418600
Forkhead box, class O (FoxO) family members are multifunctional transcription factors that are involved in several metabolic processes, including energy metabolism, apoptosis, DNA repair, and oxidative stress. However, their roles...
6.
Joung E, Cao L, Lee B, Gwon W, Park S, Kim H
Inflammation . 2021 May; 44(5):2120-2131. PMID: 34050497
Sargahydroquinoic acid (SHQA) is a major plastoquinone in Sargassum macrocarpum and has shown the capacity to prevent inflammation and oxidative stress. However, the protective mechanisms were unclear. The molecular mechanisms...
7.
Cao L, Lee S, Park S, Kim H
Exp Gerontol . 2021 May; 151:111406. PMID: 34022274
Aim: The effects of sargahydroquinoic acid (SHQA) on cellular senescence and the underlying mechanisms were investigated using human umbilical vascular endothelial cells (HUVECs). Methods: SHQA or DMSO was supplemented into...
8.
Yoon J, Lee N, Youn K, Jo M, Kim H, Lee D, et al.
Mar Drugs . 2021 Apr; 19(3). PMID: 33804171
The proteolytic processing of amyloid precursor protein (APP) by β-secretase (BACE1) and γ-secretase releases amyloid-β peptide (Aβ), which deposits in amyloid plaques and contributes to the initial causative events of...
9.
Siboro S, Anugrah D, Ramesh K, Park S, Kim H, Lim K
Carbohydr Polym . 2021 Mar; 260:117779. PMID: 33712135
Task-specific drug release is essential in the development of hydrogels as drug delivery systems. The aim of the study is to report the effect of porosity on alginate hydrogels, which...
10.
Cao L, Lee S, Lim K, Kim H
Mar Drugs . 2020 Nov; 18(11). PMID: 33218066
Aging is a major risk factor for many chronic diseases, such as cancer, cardiovascular disease, and diabetes. The exact mechanisms underlying the aging process are not fully elucidated. However, a...