Hwayoung Yun
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Explore the profile of Hwayoung Yun including associated specialties, affiliations and a list of published articles.
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69
Citations
694
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Recent Articles
1.
Yoo J, Jo J, Ha S, Kwak J, Kim M, Kim J, et al.
Biol Pharm Bull
. 2024 Sep;
47(9):1557-1564.
PMID: 39313392
Oxidative stress plays a crucial role in the development and progression of various kidney diseases. Nuclear factor erythroid 2-related factor 2 (NRF2) is the primary transcription factor that protects cells...
2.
Nguyen L, Cho Y, Kim S, Kim Y, Kwak J, Suh J, et al.
J Med Chem
. 2024 Sep;
67(19):17608-17628.
PMID: 39259827
Metabolic dysfunction-associated steatotic liver disease (MASLD) is primarily attributed to the abnormal upregulation of hepatic lipogenesis, which is especially caused by the overactivation of the liver X receptor/sterol regulatory element-binding...
3.
Choi J, Ahn J, Bae J, Yoon M, Yun H, Koh M
ACS Synth Biol
. 2024 Aug;
13(8):2587-2599.
PMID: 39110782
Genetic code expansion (GCE) is a powerful strategy that expands the genetic code of an organism for incorporating noncanonical amino acids into proteins using engineered tRNAs and aminoacyl-tRNA synthetases (aaRSs)....
4.
Eum D, Lee C, Tran C, Lee J, Park S, Jeong M, et al.
Toxicol Res
. 2024 Jun;
40(3):409-419.
PMID: 38911538
Echinochrome A (Ech A), a marine biosubstance isolated from sea urchins, is a strong antioxidant, and its clinical form, histochrome, is being used to treat several diseases, such as ophthalmic,...
5.
Eum D, Jeong M, Park S, Kim J, Jin Y, Jo J, et al.
PLoS One
. 2024 Apr;
19(4):e0296989.
PMID: 38625901
Natural anmindenol A isolated from the marine-derived bacteria Streptomyces sp. caused potent inhibition of inducible nitric oxide synthase without any significant cytotoxicity. This compound consists of a structurally unique 3,10-dialkylbenzofulvene...
6.
Kim J, Lee S, Hong D, Yang S, Tran C, Kwak J, et al.
Neuromolecular Med
. 2024 Jan;
26(1):1.
PMID: 38294608
Parkinson's disease (PD) is a neurodegenerative disorder that results in motor impairment due to dopaminergic neuronal loss. The pathology of PD is closely associated with neuroinflammation, which can be characterized...
7.
Kim S, Son G, Seok J, Chun S, Yun H, Jang J, et al.
Life Sci
. 2023 May;
325:121744.
PMID: 37127185
Aims: Dysregulation of adrenocortical steroid (corticosteroids) biosynthesis leads to pathological conditions such as Cushing's syndrome. Although several classes of steroid biosynthesis inhibitors have been developed to treat cortisol overproduction, limitations...
8.
Jo J, Kim J, Ibrahim L, Kumar M, Iaconelli J, Tran C, et al.
Bioorg Med Chem Lett
. 2023 Apr;
89:129306.
PMID: 37116763
Activating NRF2-driven transcription with non-electrophilic small molecules represents an attractive strategy to therapeutically target disease states associated with oxidative stress and inflammation. In this study, we describe a campaign to...
9.
Han D, Kwak J, Choi E, Seo S, Vasileva E, Mishchenko N, et al.
Biomed Pharmacother
. 2023 Apr;
162:114589.
PMID: 37004327
Echinochrome A, a natural naphthoquinone pigment found in sea urchins, is increasingly being investigated for its nutritional and therapeutic value associated with antioxidant, anticancer, antiviral, antidiabetic, and cardioprotective activities. Although...
10.
Cao J, Hlaing S, Lee J, Kim J, Lee E, Kang S, et al.
ACS Appl Mater Interfaces
. 2022 Nov;
14(45):50507-50519.
PMID: 36331408
A bacteria-infected wound can lead to being life-threatening and raises a great economic burden on the patient. Here, we developed polyethylenimine 1.8k (PEI) surface modified NO-releasing polyethylenimine 25k (PEI)-functionalized graphene...