Huub C J Hoefsloot
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Explore the profile of Huub C J Hoefsloot including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Naue J, Hoefsloot H, Kloosterman A, Verschure P
Forensic Sci Int Genet
. 2017 Nov;
33:17-23.
PMID: 29175600
Analysis of human DNA methylation (DNAm) can provide additional investigative leads in crime cases, e.g. the type of tissue or body fluid, the chronological age of an individual, and differentiation...
12.
Naue J, Hoefsloot H, Mook O, Rijlaarsdam-Hoekstra L, van der Zwalm M, Henneman P, et al.
Forensic Sci Int Genet
. 2017 Aug;
31:19-28.
PMID: 28841467
The use of DNA methylation (DNAm) to obtain additional information in forensic investigations showed to be a promising and increasing field of interest. Prediction of the chronological age based on...
13.
Genome-wide mapping of transcriptional enhancer candidates using DNA and chromatin features in maize
Oka R, Zicola J, Weber B, Anderson S, Hodgman C, Gent J, et al.
Genome Biol
. 2017 Jul;
18(1):137.
PMID: 28732548
Background: While most cells in multicellular organisms carry the same genetic information, in each cell type only a subset of genes is being transcribed. Such differentiation in gene expression depends,...
14.
Monsonis Centelles S, Hoefsloot H, Khakimov B, Ebrahimi P, Lind M, Kristensen M, et al.
Anal Chem
. 2017 Jul;
89(15):8004-8012.
PMID: 28692288
Lipoprotein profiling of human blood by H nuclear magnetic resonance (NMR) spectroscopy is a rapid and promising approach to monitor health and disease states in medicine and nutrition. However, lack...
15.
Kutzera J, Smilde A, Wilderjans T, Hoefsloot H
PLoS One
. 2015 Oct;
10(10):e0139704.
PMID: 26448546
Protein interaction in cells can be described at different levels. At a low interaction level, proteins function together in small, stable complexes and at a higher level, in sets of...
16.
Timmerman M, Hoefsloot H, Smilde A, Ceulemans E
Metabolomics
. 2015 Sep;
11(5):1265-1276.
PMID: 26366136
In omics research often high-dimensional data is collected according to an experimental design. Typically, the manipulations involved yield differential effects on subsets of variables. An effective approach to identify those...
17.
Borirak O, de Koning L, van der Woude A, Hoefsloot H, Dekker H, Roseboom W, et al.
Biotechnol Biofuels
. 2015 Aug;
8:111.
PMID: 26246854
Background: This study aimed at exploring the molecular physiological consequences of a major redirection of carbon flow in so-called cyanobacterial cell factories: quantitative whole-cell proteomics analyses were carried out on...
18.
Hasdemir D, Hoefsloot H, Smilde A
BMC Syst Biol
. 2015 Jul;
9:32.
PMID: 26152206
Background: Most ordinary differential equation (ODE) based modeling studies in systems biology involve a hold-out validation step for model validation. In this framework a pre-determined part of the data is...
19.
Borirak O, Rolfe M, de Koning L, Hoefsloot H, Bekker M, Dekker H, et al.
Biochim Biophys Acta
. 2015 Jun;
1854(10 Pt A):1269-79.
PMID: 26049081
Time-series transcript- and protein-profiles were measured upon initiation of carbon catabolite repression in Escherichia coli, in order to investigate the extent of post-transcriptional control in this prototypical response. A glucose-limited...
20.
Saccenti E, van Duynhoven J, Jacobs D, Smilde A, Hoefsloot H
PLoS One
. 2015 Mar;
10(3):e0119856.
PMID: 25786212
The ability to restore homeostasis upon environmental challenges has been proposed as a measure for health. Metabolic profiling of plasma samples during the challenge response phase should offer a profound...