Johan A Westerhuis
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Explore the profile of Johan A Westerhuis including associated specialties, affiliations and a list of published articles.
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60
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1913
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Recent Articles
1.
Llambrich M, van der Kloet F, Semente L, Rodrigues A, Samanipour S, Stefanuto P, et al.
Brief Bioinform
. 2025 Mar;
26(2).
PMID: 40037642
Comprehensive 2D gas chromatography coupled with mass spectrometry (GC × GC-MS) is a powerful analytical technique. However, the complexity and volume of data generated pose significant challenges for data processing...
2.
Isaiah S, Westerhuis J, Loots D, Solomons R, Tutu van Furth M, van Elsland S, et al.
Sci Rep
. 2024 Aug;
14(1):19471.
PMID: 39174657
Tuberculous meningitis (TBM)-the extrapulmonary form of tuberculosis, is the most severe complication associated with tuberculosis, particularly in infants and children. The gold standard for the diagnosis of TBM requires cerebrospinal...
3.
Abegaz F, Abedini D, White F, Guerrieri A, Zancarini A, Dong L, et al.
Sci Rep
. 2024 May;
14(1):12433.
PMID: 38816496
Comparing the abundance of microbial communities between different groups or obtained under different experimental conditions using count sequence data is a challenging task due to various issues such as inflated...
4.
Erdos B, Westerhuis J, Adriaens M, ODonovan S, Xie R, Singh-Povel C, et al.
PLoS Comput Biol
. 2023 Jun;
19(6):e1011221.
PMID: 37352364
The intricate dependency structure of biological "omics" data, particularly those originating from longitudinal intervention studies with frequently sampled repeated measurements renders the analysis of such data challenging. The high-dimensionality, inter-relatedness...
5.
Leygeber S, Grossmann J, Diez-Simon C, Karu N, Dubbelman A, Harms A, et al.
Metabolites
. 2022 Dec;
12(12).
PMID: 36557232
Trained sensory panels are regularly used to rate food products but do not allow for data-driven approaches to steer food product development. This study evaluated the potential of a molecular-based...
6.
Molendijk J, Kolka C, Cairns H, Brosda S, Mohamed A, Shah A, et al.
Clin Transl Med
. 2022 May;
12(5):e810.
PMID: 35560527
Background: The risk of esophageal adenocarcinoma (EAC) is associated with gastro-esophageal reflux disease (GERD) and obesity. Lipid metabolism-targeted therapies decrease the risk of progressing from Barrett's esophagus (BE) to EAC,...
7.
Kim B, Westerhuis J, Smilde A, Flokova K, Suleiman A, Kuramae E, et al.
FEMS Microbiol Ecol
. 2022 Feb;
98(2).
PMID: 35137050
Strigolactones are endogenous plant hormones regulating plant development and are exuded into the rhizosphere when plants experience nutrient deficiency. There, they promote the mutualistic association of plants with arbuscular mycorrhizal...
8.
Madssen T, Giskeodegard G, Smilde A, Westerhuis J
PLoS Comput Biol
. 2021 Nov;
17(11):e1009585.
PMID: 34752455
Longitudinal intervention studies with repeated measurements over time are an important type of experimental design in biomedical research. Due to the advent of "omics"-sciences (genomics, transcriptomics, proteomics, metabolomics), longitudinal studies...
9.
Davarzani N, Diez-Simon C, Grossmann J, Jacobs D, van Doorn R, van den Berg M, et al.
Metabolomics
. 2021 Aug;
17(9):77.
PMID: 34435244
Introduction: The relationship between the chemical composition of food products and their sensory profile is a complex association confronting many challenges. However, new untargeted methodologies are helping correlate metabolites with...
10.
Zancarini A, Westerhuis J, Smilde A, Bouwmeester H
Curr Opin Biotechnol
. 2021 Jul;
70:255-261.
PMID: 34242993
The plant microbiome plays an essential role in supporting plant growth and health, but plant molecular mechanisms underlying its recruitment are still unclear. Multi-omics data integration methods can be used...