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Bas Teusink

Explore the profile of Bas Teusink including associated specialties, affiliations and a list of published articles. Areas
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Articles 134
Citations 3541
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Recent Articles
1.
Teusink B, Planque R, Bruggeman F
Nat Metab . 2025 Jan; 7(1):8-10. PMID: 39762389
No abstract available.
2.
Bruggeman F, Remeijer M, Droste M, Salinas L, Wortel M, Planque R, et al.
Biosystems . 2024 Nov; :105067. PMID: 39492480
Since its conception some fifty years ago, metabolic control analysis (MCA) aims to understand how cells control their metabolism by adjusting the activity of their enzymes. Here we extend its...
3.
Berkvens A, Salinas L, Remeijer M, Planque R, Teusink B, Bruggeman F
Essays Biochem . 2024 Apr; 68(1):41-51. PMID: 38662439
The expression of metabolic proteins is controlled by genetic circuits, matching metabolic demands and changing environmental conditions. Ideally, this regulation brings about a competitive level of metabolic fitness. Understanding how...
4.
Botman D, Kanagasabapathi S, Rep M, van Rossum K, Tutucci E, Teusink B
Biochim Biophys Acta Mol Cell Res . 2024 Mar; 1871(4):119706. PMID: 38521467
S. cerevisiae (or budding yeast) is an important micro-organism for sucrose-based fermentation in biotechnology. Yet, it is largely unknown how budding yeast adapts to sucrose transitions. Sucrose can only be...
5.
Bexkens M, Martin O, van den Heuvel J, Schmitz M, Teusink B, Bakker B, et al.
Int J Parasitol . 2024 Mar; 54(7):367-378. PMID: 38492780
Lactate dehydrogenase (LDH) from Schistosoma mansoni has peculiar properties for a eukaryotic LDH. Schistosomal LDH (SmLDH) isolated from schistosomes, and the recombinantly expressed protein, are strongly inhibited by ATP, which...
6.
Luzia L, Battjes J, Zwering E, Jansen D, Melkonian C, Teusink B
iScience . 2024 Jan; 27(1):108767. PMID: 38235328
adjusts its metabolism based on nutrient availability, typically transitioning from glucose fermentation to ethanol respiration as glucose becomes limiting. However, our understanding of the regulation of metabolism is largely based...
7.
Douwenga S, van Olst B, Boeren S, Luo Y, Lai X, Teusink B, et al.
Microbiol Spectr . 2023 Oct; 11(6):e0224823. PMID: 37888986
The availability of nutrients to microorganisms varies considerably between different environments, and changes can occur rapidly. As a general rule, a fast growth rate-typically growth on glucose-is associated with the...
8.
Bendig T, Ulmer A, Luzia L, Muller S, Sahle S, Bergmann F, et al.
J Biotechnol . 2023 Aug; 374:90-100. PMID: 37572793
The fermentation process of milk to yoghurt using Lactobacillus delbrueckii subsp. bulgaricus in co-culture with Streptococcus thermophilus is hallmarked by the breakdown of lactose to organic acids such as lactate....
9.
Bruggeman F, Teusink B, Steuer R
Bioessays . 2023 Aug; 45(10):e2300015. PMID: 37559168
Microbial systems biology has made enormous advances in relating microbial physiology to the underlying biochemistry and molecular biology. By meticulously studying model microorganisms, in particular Escherichia coli and Saccharomyces cerevisiae,...
10.
Botman D, Kanagasabapathi S, Savakis P, Teusink B
FEMS Yeast Res . 2023 May; 23. PMID: 37173282
Budding yeast uses the TORC1-Sch9p and cAMP-PKA signalling pathways to regulate adaptations to changing nutrient environments. Dynamic and single-cell measurements of the activity of these cascades will improve our understanding...