Hugh H Reid
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Explore the profile of Hugh H Reid including associated specialties, affiliations and a list of published articles.
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56
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2406
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Recent Articles
1.
Zhang J, Chaurasia P, Nguyen A, Huang Z, Nguyen T, Xu H, et al.
Sci Immunol
. 2025 Feb;
10(104):eadp5016.
PMID: 39982976
The interaction between the CD4/CD8 co-receptors and LCK (an Src family tyrosine kinase) is thought to augment T cell activation upon recognition of peptide-loaded major histocompatibility complexes (pMHCs). How this...
2.
Hardy M, Russell A, Henneken L, Tanner G, Bekes F, Brown I, et al.
Gut
. 2025 Feb;
PMID: 39961645
Background: Oat ingestion in coeliac disease (CD) is generally regarded as safe but can trigger enteropathy and T cells specific for oat avenin in the gut and blood of some...
3.
Tran M, Lim J, Loh T, Mannering S, Rossjohn J, Reid H
J Biol Chem
. 2024 Jul;
300(9):107612.
PMID: 39074636
Type 1 diabetes (T1D) is a T cell-mediated autoimmune disease that has a strong HLA association, where a number of self-epitopes have been implicated in disease pathogenesis. Human pancreatic islet-infiltrating...
4.
Loh T, Lim J, Jones C, Dao H, Tran M, Baker D, et al.
Nat Commun
. 2024 Jul;
15(1):6201.
PMID: 39043656
CD4 T cells recognising citrullinated self-epitopes presented by HLA-DRB1 bearing the shared susceptibility epitope (SE) are implicated in rheumatoid arthritis (RA). However, the underlying T cell receptor (TCR) determinants of...
5.
Tran M, Ciacchi L, Ciacchi L, Reid H
Immunol Cell Biol
. 2024 Mar;
102(5):341-346.
PMID: 38441372
To educate members of the blind, low-vision and diverse needs communities on the pathogenesis of the chronic autoimmune disease, type 1 diabetes, members of our team with research expertise in...
6.
Henneken L, Loh T, Ciacchi L, Ciacchi L, Lim J, Reid H, et al.
Immunol Cell Biol
. 2023 Dec;
102(5):331-335.
PMID: 38111272
As part of the Monash Sensory Science Exhibition, our team guided participants through a multisensory journey unraveling coeliac disease development and pathology. Through tactile and sensory exhibits, we showed how...
7.
Ciacchi L, van de Garde M, Ladell K, Farenc C, Poelen M, Miners K, et al.
Immunity
. 2023 Apr;
56(5):1082-1097.e6.
PMID: 37100059
CD4 T cell-mediated immunity against Streptococcus pneumoniae (pneumococcus) can protect against recurrent bacterial colonization and invasive pneumococcal diseases (IPDs). Although such immune responses are common, the pertinent antigens have remained...
8.
Klobuch S, Lim J, van Balen P, Kester M, de Klerk W, de Ru A, et al.
Proc Natl Acad Sci U S A
. 2022 Nov;
119(49):e2214331119.
PMID: 36442096
Human leukocyte antigen (HLA) molecules present small peptide antigens to T cells, thereby allowing them to recognize pathogen-infected and cancer cells. A central dogma over the last 50+ y is...
9.
Sonigra A, Nel H, Wehr P, Ramnoruth N, Patel S, van Schie K, et al.
JCI Insight
. 2022 Oct;
7(20).
PMID: 36278483
BACKGROUNDAntigen-specific regulation of autoimmune disease is a major goal. In seropositive rheumatoid arthritis (RA), T cell help to autoreactive B cells matures the citrullinated (Cit) antigen-specific immune response, generating RA-specific...
10.
Ciacchi L, Reid H, Rossjohn J
Curr Opin Struct Biol
. 2022 Mar;
74:102349.
PMID: 35272251
Celiac disease (CeD) is a human leukocyte antigen (HLA)-linked autoimmune-like disorder that is triggered by the ingestion of gluten or related storage proteins. The majority of CeD patients are HLA-DQ2.5,...