Huan Qiao
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Explore the profile of Huan Qiao including associated specialties, affiliations and a list of published articles.
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30
Citations
501
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Recent Articles
11.
Gao R, Li D, Xun J, Zhou W, Li J, Wang J, et al.
Theranostics
. 2019 Jan;
8(22):6248-6262.
PMID: 30613295
CD44 is a single-pass cell surface glycoprotein that is distinguished as the first molecule used to identify cancer stem cells in solid tumors based on its expression. In this regard,...
12.
Gao R, Liu Y, Li D, Xun J, Zhou W, Wang P, et al.
Cell Physiol Biochem
. 2018 Nov;
50(6):2108-2123.
PMID: 30415245
Background/aims: The bi-functional enzyme 6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase-4 (PFKFB4) is highly expressed in many types of cancer and its requirement for tumor survival has been demonstrated in glioma, lung, and prostate cancers....
13.
Fan P, Narzisi G, Jayaprakash A, Venturini E, Robine N, Smibert P, et al.
Proc Natl Acad Sci U S A
. 2018 Jun;
115(26):E6030-E6038.
PMID: 29875142
In ∼30% of patients with -mutant lung adenocarcinomas whose disease progresses on EGFR inhibitors, the basis for acquired resistance remains unclear. We have integrated transposon mutagenesis screening in an -mutant...
14.
Qiao H, Lovly C
Cancer Discov
. 2016 Oct;
6(10):1084-1086.
PMID: 27698100
In the setting of recent exciting clinical results and numerous ongoing trials, Gainor and colleagues explored mechanisms of acquired resistance to first- and second-generation ALK inhibitors in ALK-rearranged non-small cell...
15.
Qiao H, Liu Y, Veach R, Wylezinski L, Hawiger J
J Biol Chem
. 2014 Jun;
289(32):21973-83.
PMID: 24958727
A hallmark of inflammation, increased vascular permeability, is induced in endothelial cells by multiple agonists through stimulus-coupled assembly of the CARMA3 signalosome, which contains the adaptor protein BCL10. Previously, we...
16.
Qiao H, May J
PLoS One
. 2012 Apr;
7(4):e35746.
PMID: 22532872
Transcription of the ascorbate transporter, SVCT2, is driven by two distinct promoters in exon 1 of the transporter sequence. The exon 1a promoter lacks a classical transcription start site and...
17.
Qiao H, May J
Biochem J
. 2011 Jul;
440(1):73-84.
PMID: 21770893
SVCT2 (sodium-vitamin C co-transporter 2) is the major transporter mediating vitamin C uptake in most organs. Its expression is driven by two promoters (CpG-poor exon 1a promoter and CpG-rich exon...
18.
Qiao H, May J
Free Radic Biol Med
. 2011 Feb;
50(9):1196-209.
PMID: 21335086
The sodium-dependent vitamin C transporter (SVCT) 2 is crucial for ascorbate uptake in metabolically active and specialized tissues. This study focused on the gene regulation of SVCT2 exon 1b, which...
19.
May J, Qu Z, Qiao H
Am J Physiol Cell Physiol
. 2009 May;
297(1):C169-78.
PMID: 19419995
To determine how ascorbic acid moves from the bloodstream into tissues, we assessed transfer of the vitamin across the barrier generated by EA.hy926 endothelial cells when these were cultured on...
20.
Qiao H, Li L, Qu Z, May J
Biofactors
. 2009 Apr;
35(3):306-13.
PMID: 19396871
Endothelial cells respond to hypoxia by decreased degradation of hypoxia-inducible factor 1alpha (HIF-1alpha), accumulation of which leads to increased transcription of numerous proteins involved in cell growth and survival. Ascorbic...