Hsiang-I Liao
Overview
Explore the profile of Hsiang-I Liao including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
559
Followers
0
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Recent Articles
1.
Nathanson D, Armijo A, Tom M, Li Z, Dimitrova E, Austin W, et al.
J Exp Med
. 2014 Feb;
211(3):473-86.
PMID: 24567448
Pharmacological targeting of metabolic processes in cancer must overcome redundancy in biosynthetic pathways. Deoxycytidine (dC) triphosphate (dCTP) can be produced both by the de novo pathway (DNP) and by the...
2.
Murphy J, Armijo A, Nomme J, Lee C, Smith Q, Li Z, et al.
J Med Chem
. 2013 Aug;
56(17):6696-708.
PMID: 23947754
Combined inhibition of ribonucleotide reductase and deoxycytidine kinase (dCK) in multiple cancer cell lines depletes deoxycytidine triphosphate pools leading to DNA replication stress, cell cycle arrest, and apoptosis. Evidence implicating...
3.
Wu T, Liao H, Tong L, Leang R, Smith G, Sun R
J Biomed Biotechnol
. 2011 Jan;
2011:926258.
PMID: 21197474
Here we describe the cloning of a sequenced WUMS isolate of murine gammaherpesvirus-68 (MHV-68, γHV-68, also known as MuHV-4) as a bacterial artificial chromosome (BAC). We engineered the insertion of...
4.
Ishikawa F, Curreli M, Olson C, Liao H, Sun R, Roberts R, et al.
ACS Nano
. 2010 Oct;
4(11):6914-22.
PMID: 21028792
Biosensors utilizing carbon nanotube field-effect transistors have a tremendous potential to serve as the basis for the next generation of diagnostic systems. While nanotubes have been employed in the fabrication...
5.
Toy G, Austin W, Liao H, Cheng D, Singh A, Campbell D, et al.
Proc Natl Acad Sci U S A
. 2010 Jan;
107(12):5551-6.
PMID: 20080663
Deoxycytidine kinase (dCK) is a rate-limiting enzyme in deoxyribonucleoside salvage, a metabolic pathway that recycles products of DNA degradation. dCK phosphorylates and therefore activates nucleoside analog prodrugs frequently used in...
6.
Ishikawa F, Chang H, Curreli M, Liao H, Olson C, Chen P, et al.
ACS Nano
. 2009 May;
3(5):1219-24.
PMID: 19422193
Antibody mimic proteins (AMPs) are polypeptides that bind to their target analytes with high affinity and specificity, just like conventional antibodies, but are much smaller in size (2-5 nm, less...
7.
Liao H, Olson C, Hwang S, Deng H, Wong E, Baric R, et al.
J Biol Chem
. 2009 Apr;
284(26):17512-20.
PMID: 19364769
The nucleocapsid (N) protein of severe acute respiratory syndrome (SARS) coronavirus plays important roles in both viral replication and modulation of host cell processes. New ligands that target the N...
8.
Olson C, Liao H, Sun R, Roberts R
ACS Chem Biol
. 2008 Jul;
3(8):480-5.
PMID: 18590330
The complexity of the human proteome is greatly expanded by post-translational modifications. New tools capable of recognizing these modifications in a sequence-specific fashion provide a route to purify these modified...
9.
Cole A, Thapa D, Gabayan V, Liao H, Liu L, Ganz T
J Leukoc Biol
. 2005 Oct;
78(5):1081-5.
PMID: 16204648
Lysozyme is a ubiquitous and abundant, cationic, antimicrobial polypeptide of leukocytes and epithelia, but its biological function in host defense is largely unexplored. To ascertain the role of lysozyme during...
10.
Jia Q, Chernishof V, Bortz E, McHardy I, Wu T, Liao H, et al.
J Virol
. 2005 Mar;
79(8):5129-41.
PMID: 15795297
Murine gammaherpesvirus 68 (MHV-68) has been developed as a model for the human gammaherpesviruses Epstein-Barr virus and human herpesvirus 8/Kaposi's sarcoma-associated herpesvirus (HHV-8/KSHV), which are associated with several types of...