Hrishikesh S Kulkarni
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Explore the profile of Hrishikesh S Kulkarni including associated specialties, affiliations and a list of published articles.
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66
Citations
1047
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Recent Articles
1.
Liao F, Zhou D, Cano M, Liu Z, Scozzi D, Tague L, et al.
Sci Transl Med
. 2025 Feb;
17(784):eadp1349.
PMID: 39908350
How pathogens inhibit transplant tolerance remains unclear. Here, we found that infection, but not other common bacterial respiratory infections, increases antibody-mediated rejection (AMR) risk in recipients of lung transplants. To...
2.
Kulkarni H, Tague L, Calabrese D, Liao F, Liu Z, Garnica L, et al.
bioRxiv
. 2024 Nov;
PMID: 39605452
A greater understanding of chronic lung allograft dysfunction (CLAD) pathobiology, the primary cause of mortality after lung transplantation, is needed to improve outcomes. The complement system links innate to adaptive...
3.
Earhart A, Aponte Alburquerque R, Starick M, Nallapu A, Garnica L, Ozanturk A, et al.
bioRxiv
. 2024 Nov;
PMID: 39554000
Complement protein C3 is crucial for immune responses in mucosal sites such as the lung, where it aids in microbe elimination and enhances inflammation. While trained immunity - enhanced secondary...
4.
Lehmann M, Krishnan R, Sucre J, Kulkarni H, Pineda R, Anderson C, et al.
Am J Respir Cell Mol Biol
. 2024 Nov;
PMID: 39499861
The urgent need for effective treatments for acute and chronic lung diseases underscores the significance of developing innovative preclinical human research tools. The 2023 ATS Workshop on Precision Cut Lung...
5.
Kulkarni D, Starick M, Aponte Alburquerque R, Kulkarni H
Mucosal Immunol
. 2024 Jun;
17(4):739-751.
PMID: 38838816
The complement system is an evolutionarily conserved arm of innate immunity, which forms one of the first lines of host response to pathogens and assists in the clearance of debris....
6.
Kulkarni H
J Clin Invest
. 2024 Jun;
134(11).
PMID: 38828725
Although antibody-mediated lung damage is a major factor in transfusion-related acute lung injury (ALI), autoimmune lung disease (for example, coatomer subunit α [COPA] syndrome), and primary graft dysfunction following lung...
7.
Earhart A, Kulkarni H
Am J Respir Cell Mol Biol
. 2024 May;
71(3):259-261.
PMID: 38717817
No abstract available.
8.
Sahu S, Maurya R, Kulkarni H
DNA Cell Biol
. 2024 Feb;
43(4):153-157.
PMID: 38324102
The complement system is a family of proteins that facilitate immune resistance by attacking microbes to decrease pathogen burden. As a result, deficiencies of certain complement proteins result in recurrent...
9.
Kulkarni D, Rusconi B, Floyd A, Joyce E, Talati K, Kousik H, et al.
Gut Microbes
. 2023 Nov;
15(2):2284240.
PMID: 38036944
Obesity and the metabolic syndrome are complex disorders resulting from multiple factors including genetics, diet, activity, inflammation, and gut microbes. Animal studies have identified roles for each of these, however...
10.
January S, Hubbard J, Fester K, Dubrawka C, Vazquez Guillamet R, Kulkarni H, et al.
J Pharm Pract
. 2023 Nov;
37(5):1170-1174.
PMID: 37923307
The renin-angiotensin-aldosterone system (RAAS) is responsible for a multitude of physiological functions, including immunological effects such as promotion of TGF-β and upregulation of IL-6 and IL-8 which are also implicated...