John P Atkinson
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Explore the profile of John P Atkinson including associated specialties, affiliations and a list of published articles.
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184
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8505
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Recent Articles
1.
Wu X, Liszewski M, Java A, Atkinson J
Ann Blood
. 2025 Feb;
8.
PMID: 39949759
The complement system is a critical innate immune defense mechanism that also facilitates antigen recognition as well as antibody production through the adaptive immune response. Overall, complement activation contributes to...
2.
Ren Z, Bao J, Zhao S, Pozzi N, Wedner H, Wedner H, et al.
JCI Insight
. 2025 Jan;
10(4).
PMID: 39823539
Hereditary angioedema is an autosomal dominant disorder caused by defects in C1-esterase inhibitor (C1-INH), resulting in poorly controlled activation of the kallikrein-kinin system and bradykinin overproduction. C1-INH is a heavily...
3.
Understanding rare genetic variants within the terminal pathway of complement system in preeclampsia
Lokki A, Triebwasser M, Daly E, Kurki M, Perola M, Auro K, et al.
Genes Immun
. 2024 Dec;
26(1):22-26.
PMID: 39690307
Preeclampsia is a common multifactorial disease of pregnancy. Dysregulation of complement activation is among emerging candidates responsible for disease pathogenesis. In a targeted exomic sequencing study of 609 women with...
4.
Kulkarni H, Tague L, Calabrese D, Liao F, Liu Z, Garnica L, et al.
bioRxiv
. 2024 Nov;
PMID: 39605452
A greater understanding of chronic lung allograft dysfunction (CLAD) pathobiology, the primary cause of mortality after lung transplantation, is needed to improve outcomes. The complement system links innate to adaptive...
5.
Praneechit H, Thiemmeca S, Prayongkul D, Kongmanas K, Mairiang D, Punyadee N, et al.
mBio
. 2024 Nov;
15(12):e0150524.
PMID: 39540772
Dengue virus (DENV) infection poses a significant global health threat, yet our understanding of its immunopathogenesis remains incomplete due to limitations of existing models. Here, we establish an whole-blood model...
6.
Pizzato H, Alonso-Guallart P, Woods J, Johannesson B, Connelly J, Fehniger T, et al.
Stem Cell Reports
. 2024 Mar;
19(4):596.
PMID: 38518782
No abstract available.
7.
Seddon J, De D, Casazza W, Cheng S, Punzo C, Daly M, et al.
Front Genet
. 2024 Feb;
14:1274743.
PMID: 38348408
Age-related macular degeneration (AMD) is the leading cause of central vision loss in the elderly. One-third of the genetic contribution to this disease remains unexplained. We analyzed targeted sequencing data...
8.
Lee S, Crosnier C, Valenzuela-Leon P, Dizon B, Atkinson J, Mu J, et al.
Proc Natl Acad Sci U S A
. 2024 Jan;
121(5):e2316304121.
PMID: 38261617
The discovery that Africans were resistant to infection by () led to the conclusion that invasion relied on the Duffy Binding Protein (PvDBP) interacting with the Duffy Antigen Receptor for...
9.
Pizzato H, Alonso-Guallart P, Woods J, Connelly J, Fehniger T, Atkinson J, et al.
Stem Cell Reports
. 2024 Jan;
19(2):299-313.
PMID: 38215755
Successful allogeneic human pluripotent stem cell (hPSC)-derived therapies must overcome immunological rejection by the recipient. To build reagents to define these barriers, we genetically ablated β2M, TAP1, CIITA, CD74, MICA,...
10.
Pizzato H, Alonso-Guallart P, Woods J, Johannesson B, Connelly J, Fehniger T, et al.
bioRxiv
. 2023 Jul;
PMID: 37425790
Allogeneic human pluripotent stem cell (hPSC)-derived cells and tissues for therapeutic transplantation must necessarily overcome immunological rejection by the recipient. To define these barriers and to create cells capable of...