Howard E Boudreau
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Explore the profile of Howard E Boudreau including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
357
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0
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Recent Articles
1.
Boudreau H, Robinson J, Kasid U
Methods Mol Biol
. 2023 May;
2660:295-310.
PMID: 37191806
DEPDC1B (aliases BRCC3, XTP8, XTP1) is a DEP (Dishevelled, Egl-1, Pleckstrin) and Rho-GAP-like domains containing predominately membrane-associated protein. Earlier, we and others have reported that DEPDC1B is a downstream effector...
2.
Boudreau H, Korzeniowska A, Leto T
Free Radic Biol Med
. 2023 Feb;
199:17-25.
PMID: 36804453
Previously, we showed wild-type (WT) and mutant (mt) forms of p53 differentially regulate ROS generation by NADPH oxidase-4 (NOX4). We found that WT-p53 suppresses TGF-β-induced NOX4, ROS production, and cell...
3.
Ma W, Boudreau H, Leto T
Antioxidants (Basel)
. 2021 Feb;
10(2).
PMID: 33557266
Previously, we have shown TGF-β-induced NOX4 expression is involved in the epithelial-to-mesenchymal transition (EMT), a process critical for cancer metastasis, and that wild-type (WT) and mutant (Mut) p53 have divergent...
4.
Boudreau H, Leto T
Methods Mol Biol
. 2019 Jun;
1982:473-485.
PMID: 31172490
There is mounting evidence indicating that reactive oxygen species (ROS) play a crucial role in cell migration and invasion. Our previous studies have demonstrated the NADPH oxidase (NOX) family of...
5.
Sugamata R, Donko A, Murakami Y, Boudreau H, Qi C, Kwon J, et al.
J Immunol
. 2018 Dec;
202(2):428-440.
PMID: 30559322
Engagement of the BCR with Ags triggers signaling pathways for commitment of B lymphocyte responses that can be regulated, in part, by reactive oxygen species. To investigate the functional relevance...
6.
Moody T, Lee L, Iordanskaia T, Ramos-Alvarez I, Moreno P, Boudreau H, et al.
Peptides
. 2018 Oct;
120:170017.
PMID: 30273693
Pituitary adenylate cyclase activating polypeptide (PACAP) is a growth factor for lung cancer cells. PACAP-27 or PACAP-38 binds with high affinity to non-small cell lung cancer (NSCLC) cells, causing elevated...
7.
Boudreau H, Ma W, Korzeniowska A, Park J, Bhagwat M, Leto T
Oncotarget
. 2017 Jun;
8(27):44379-44397.
PMID: 28574838
Previously, we showed wild-type (WT) and mutant (mut) p53 differentially regulate reactive oxygen species (ROS) generation by NADPH oxidase-4 (NOX4): p53-WT suppresses TGFβ-induced NOX4, ROS and cell migration, whereas tumor-associated...
8.
Kwon J, Wang A, Burke D, Boudreau H, Lekstrom K, Korzeniowska A, et al.
Free Radic Biol Med
. 2016 Apr;
96:99-115.
PMID: 27094494
Nox1 is an abundant source of reactive oxygen species (ROS) in colon epithelium recently shown to function in wound healing and epithelial homeostasis. We identified Peroxiredoxin 6 (Prdx6) as a...
9.
Donko A, Morand S, Korzeniowska A, Boudreau H, Zana M, Hunyady L, et al.
Free Radic Biol Med
. 2014 May;
73:190-200.
PMID: 24853759
In the thyroid gland Duox2-derived H2O2 is essential for thyroid hormone biosynthesis. Several patients were identified with partial or severe iodide organification defects caused by mutation in the gene for...
10.
Rada B, Boudreau H, Park J, Leto T
Am J Respir Cell Mol Biol
. 2013 Aug;
50(1):125-34.
PMID: 23962049
Oxidative stress has been implicated in the pathogenesis of bronchial asthma. Besides granulocytes, the airway epithelium can produce large amounts of reactive oxygen species and can contribute to asthma-related oxidative...