Hope A Sansing
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Explore the profile of Hope A Sansing including associated specialties, affiliations and a list of published articles.
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10
Citations
179
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Recent Articles
1.
Lee K, Chiu K, Sansing H, Didier P, Lackner A, MacLean A
J Neurovirol
. 2016 Jun;
22(6):831-839.
PMID: 27273075
Flaviviruses, including Zika and dengue (DENV), pose a serious global threat to human health. Of the 50+ million humans infected with DENV annually, approximately 1-3 % progress to severe disease...
2.
Lee K, Chiu K, Renner N, Sansing H, Didier P, MacLean A
J Neurovirol
. 2014 Jun;
20(5):474-84.
PMID: 24970236
Cortical function is disrupted in neuroinflammatory disorders, including HIV-associated neurocognitive disorders (HAND). Astrocyte dysfunction includes retraction of foot processes from the blood-brain barrier and decreased removal of neurotransmitters from synaptic...
3.
Lee K, Chiu K, Sansing H, Didier P, Ficht T, Arenas-Gamboa A, et al.
Front Cell Infect Microbiol
. 2013 Dec;
3:86.
PMID: 24350061
Brucella melitensis, a bacterial pathogen and agent of epizootic abortion causes multiple pathologies in humans as well as a number of agriculturally important animal species. Clinical human brucellosis manifests as...
4.
Snook E, Fisher-Perkins J, Sansing H, Lee K, Alvarez X, MacLean A, et al.
Am J Pathol
. 2013 Dec;
184(2):382-96.
PMID: 24316110
Globoid cell leukodystrophy is a lysosomal storage disease characterized by the loss of galactocerebrosidase. Galactocerebrosidase loss leads to the accumulation of psychosine and subsequent oligodendrocyte cell death, demyelination, macrophage recruitment,...
5.
Lee K, Chiu K, Sansing H, Inglis F, Baker K, MacLean A
PLoS One
. 2013 Aug;
8(7):e69980.
PMID: 23922882
Background: Self-injurious behavior (SIB) is a complex condition that exhibits a spectrum of abnormal neuropsychological and locomotor behaviors. Mechanisms for neuropathogenesis could include irregular immune activation, host soluble factors, and...
6.
Renner N, Sansing H, Inglis F, Mehra S, Kaushal D, Lackner A, et al.
J Cell Physiol
. 2012 Nov;
228(6):1284-94.
PMID: 23154943
The foot processes of astrocytes cover over 60% of the surface of brain microvascular endothelial cells, regulating tight junction integrity. Retraction of astrocyte foot processes has been postulated to be...
7.
Renner N, Sansing H, Morici L, Inglis F, Lackner A, MacLean A
J Neurovirol
. 2012 Apr;
18(3):213-21.
PMID: 22535448
HIV infection in the brain and the resultant encephalitis affect approximately one third of individuals infected with HIV, regardless of treatment with antiretroviral drugs. Microglia are the resident phagocytic cell...
8.
Sansing H, Renner N, MacLean A
J Neurosci Methods
. 2012 Apr;
207(1):91-6.
PMID: 22484463
The blood-brain barrier (BBB) is increasingly being recognized as a site of special scientific importance. Numerous models of the BBB have been constructed over the past years with increasingly mechanistic...
9.
Eberle K, Sansing H, Szaniszlo P, Resto V, Berrier A
PLoS One
. 2011 Jul;
6(6):e21496.
PMID: 21720550
Extracellular matrix factors within the tumor microenvironment that control resistance to chemotherapeutics are poorly understood. This study focused on understanding matrix adhesion pathways that control the oral carcinoma response to...
10.
Sansing H, Sarkeshik A, Yates J, Patel V, Gutkind J, Yamada K, et al.
Biochem Biophys Res Commun
. 2011 Feb;
406(2):171-6.
PMID: 21291860
Ligand engagement by integrins induces receptor clustering and formation of complexes at the integrin cytoplasmic face that controls cell signaling and cytoskeletal dynamics critical for adhesion-dependent processes. This study searches...