Andrew G MacLean
Overview
Explore the profile of Andrew G MacLean including associated specialties, affiliations and a list of published articles.
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34
Citations
977
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Recent Articles
1.
Horn M, Forest S, Saied A, MacLean A
Front Aging Neurosci
. 2024 Apr;
16:1368517.
PMID: 38577492
Introduction: As the population over the age of 65 increases, rates of neurodegenerative disorders and dementias will rise - necessitating further research into the cellular and molecular mechanisms that contribute...
2.
Van Zandt A, MacLean A
J Neurovirol
. 2023 Aug;
29(4):389-399.
PMID: 37635184
Human immunodeficiency virus (HIV), the main contributor of the ongoing AIDS epidemic, remains one of the most challenging and complex viruses to target and eradicate due to frequent genome mutation...
3.
McNamara R, Zhou Y, Eason A, Landis J, Chambers M, Willcox S, et al.
J Extracell Vesicles
. 2022 Mar;
11(3):e12191.
PMID: 35234354
Extracellular vesicles (EVs) are secreted from all cell types and are intimately involved in tissue homeostasis. They are being explored as vaccine and gene therapy platforms, as well as potential...
4.
Horn M, MacLean A
Front Cell Neurosci
. 2021 Jul;
15:695899.
PMID: 34290592
Extracellular vesicles (EVs) are small, membrane-bound vesicles released by cells as a means of intercellular communication. EVs transfer proteins, nucleic acids, and other biologically relevant molecules from one cell to...
5.
Schouest B, Peterson T, Szeltner D, Scheef E, Baddoo M, Ungerleider N, et al.
J Neurovirol
. 2021 Jan;
27(1):116-125.
PMID: 33405202
Astrocytes are an early and important target of Zika virus (ZIKV) infection in the developing brain, but the impacts of infection on astrocyte function remain controversial. Given that nonhuman primate...
6.
Mancuso P, Chen C, Kaminski R, Gordon J, Liao S, Robinson J, et al.
Nat Commun
. 2020 Nov;
11(1):6065.
PMID: 33247091
Elimination of HIV DNA from infected individuals remains a challenge in medicine. Here, we demonstrate that intravenous inoculation of SIV-infected macaques, a well-accepted non-human primate model of HIV infection, with...
7.
Delery E, MacLean A
Front Cell Neurosci
. 2019 Sep;
13:396.
PMID: 31555096
While there are murine and rat choroid plexus epithelial cell cultures, a translationally relevant model for choroid plexus activation and function is still lacking. The rhesus macaque is the gold...
8.
Peterson T, MacLean A, Russell-Lodrigue K, Didier P, Weaver S, Roy C
J Med Primatol
. 2019 Apr;
48(4):257-259.
PMID: 30945306
A cynomolgus macaque (Macaca fascicularis) with a pre-existing, undiagnosed, subclinical but severe cerebral hydrocephalus was enrolled in a study of long-term immunogenicity of the IRES/CHIK vaccine. The animal began showing...
9.
Chiu K, Lee K, Robillard K, MacLean A
Methods Mol Biol
. 2019 Jan;
1938:265-276.
PMID: 30617987
With a rapidly aging population, studies of neuroinflammation and degeneration associated with eugeric aging are becoming critical. Using the unique archive at the Tulane National Primate Research Center as a...
10.
Peterson T, MacLean A
J Neuroimmune Pharmacol
. 2018 Oct;
14(1):68-93.
PMID: 30317409
Macrophages, one of the most abundant populations of leukocytes in the body, function as the first line of defense against pathogen invaders. Human Immunodeficiency virus 1 (HIV-1) remains to date...