Andrew A Lackner
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Explore the profile of Andrew A Lackner including associated specialties, affiliations and a list of published articles.
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128
Citations
4248
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Recent Articles
1.
Apetrei C, Gaufin T, Brocca-Cofano E, Sivanandham R, Sette P, He T, et al.
JCI Insight
. 2023 Jul;
8(14).
PMID: 37485874
Resolution of T cell activation and inflammation is a key determinant of the lack of SIV disease progression in African green monkeys (AGMs). Although frequently considered together, T cell activation...
2.
Lawrence S, Elser S, Torben W, Blair R, Pahar B, Aye P, et al.
PLoS Pathog
. 2022 Jun;
18(6):e1010507.
PMID: 35714165
The HIV/SIV envelope glycoprotein (Env) cytoplasmic domain contains a highly conserved Tyr-based trafficking signal that mediates both clathrin-dependent endocytosis and polarized sorting. Despite extensive analysis, the role of these functions...
3.
Maness N, Schouest B, Singapuri A, Dennis M, Gilbert M, Bohm R, et al.
Sci Rep
. 2019 Sep;
9(1):12802.
PMID: 31488856
Recent data in a nonhuman primate model showed that infants postnatally infected with Zika virus (ZIKV) were acutely susceptible to high viremia and neurological damage, suggesting the window of vulnerability...
4.
Magnani D, Rogers T, Maness N, Grubaugh N, Beutler N, Bailey V, et al.
Nat Commun
. 2018 Apr;
9(1):1624.
PMID: 29691387
Zika virus (ZIKV) infection of pregnant women is associated with pathologic complications of fetal development. Here, we infect pregnant rhesus macaques (Macaca mulatta) with a minimally passaged ZIKV isolate from...
5.
Gautam U, Foreman T, Bucsan A, Veatch A, Alvarez X, Adekambi T, et al.
Proc Natl Acad Sci U S A
. 2017 Dec;
115(1):E62-E71.
PMID: 29255022
continues to cause devastating levels of mortality due to tuberculosis (TB). The failure to control TB stems from an incomplete understanding of the highly specialized strategies that utilizes to modulate...
6.
Veazey R, Lackner A
ILAR J
. 2017 Dec;
58(2):160-171.
PMID: 29228218
Research using nonhuman primates (NHPs) as models for human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS) has resulted in tremendous achievements not only in the prevention and treatment...
7.
Swanstrom A, Del Prete G, Deleage C, Elser S, Lackner A, Hoxie J
Curr HIV Res
. 2017 Nov;
16(1):29-40.
PMID: 29173176
Background: Cellular tropism of human immunodeficiency virus (HIV-1) is closely linked to interactions between the viral envelope glycoprotein (Env) with CD4 and chemokine receptor family members, CCR5 and CXCR4. This...
8.
Foreman T, Veatch A, LoBato D, Didier P, Doyle-Meyers L, Russell-Lodrigue K, et al.
Am J Pathol
. 2017 Sep;
187(12):2811-2820.
PMID: 28935575
Failure to replace Bacille Calmette-Guerin vaccines with efficacious anti-tuberculosis (TB) vaccines have prompted outside-the-box thinking, including pulmonary vaccination to elicit local immunity. Inhalational MtbΔsigH, a stress-response-attenuated strain, protected against lethal...
9.
Pace B, Lackner A, Porter E, Pahar B
Mediators Inflamm
. 2017 Aug;
2017:5186904.
PMID: 28839349
Profound loss of CD4 T cells, progressive impairment of the immune system, inflammation, and sustained immune activation are the characteristics of human immunodeficiency virus-1 (HIV-1) infection. Innate immune responses respond...
10.
Foreman T, Mehra S, Lackner A, Kaushal D
ILAR J
. 2017 Jun;
58(2):151-159.
PMID: 28575319
Infection with Mycobacterium tuberculosis predominantly establishes subclinical latent infection over the lifetime of an individual, with a fraction of infected individuals rapidly progressing to active disease. The immune control in...