» Authors » Hiren J Joshi

Hiren J Joshi

Explore the profile of Hiren J Joshi including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 42
Citations 2189
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
21.
Joshi H, Narimatsu Y, Schjoldager K, Tytgat H, Aebi M, Clausen H, et al.
Cell . 2018 Jan; 172(3):632-632.e2. PMID: 29373833
O-glycosylation is one of the most abundant and diverse types of post-translational modifications of proteins. O-glycans modulate the structure, stability, and function of proteins and serve generalized as well as...
22.
Narimatsu Y, Joshi H, Yang Z, Gomes C, Chen Y, Lorenzetti F, et al.
Glycobiology . 2018 Jan; 28(5):295-305. PMID: 29315387
Over 200 glycosyltransferases are involved in the orchestration of the biosynthesis of the human glycome, which is comprised of all glycan structures found on different glycoconjugates in cells. The glycome...
23.
King S, Joshi H, Schjoldager K, Halim A, Madsen T, Dziegiel M, et al.
Blood Adv . 2018 Jan; 1(7):429-442. PMID: 29296958
The hemostatic system comprises platelet aggregation, coagulation, and fibrinolysis, and is critical to the maintenance of vascular integrity. Multiple studies indicate that glycans play important roles in the hemostatic system;...
24.
Joshi H, Jorgensen A, Schjoldager K, Halim A, Dworkin L, Steentoft C, et al.
Glycobiology . 2017 Dec; 28(3):131-136. PMID: 29267884
The GlycoDomainViewer is a bioinformatic tool to aid in the mining of glycoproteomic datasets from different sources and facilitate incorporation of glycosylation into studies of protein structure and function. We...
25.
Bagdonaite I, Norden R, Joshi H, King S, Vakhrushev S, Olofsson S, et al.
J Biol Chem . 2016 Apr; 291(23):12014-28. PMID: 27129252
Herpesviruses are among the most complex and widespread viruses, infection and propagation of which depend on envelope proteins. These proteins serve as mediators of cell entry as well as modulators...
26.
Neubert P, Halim A, Zauser M, Essig A, Joshi H, Zatorska E, et al.
Mol Cell Proteomics . 2016 Jan; 15(4):1323-37. PMID: 26764011
O-Mannosylation is a vital protein modification conserved from fungi to humans. Yeast is a perfect model to study this post-translational modification, because in contrast to mammalsO-mannosylation is the only type...
27.
Schjoldager K, Joshi H, Kong Y, Goth C, King S, Wandall H, et al.
EMBO Rep . 2015 Nov; 16(12):1713-22. PMID: 26566661
GalNAc-type O-glycosylation is found on most proteins trafficking through the secretory pathway in metazoan cells. The O-glycoproteome is regulated by up to 20 polypeptide GalNAc-Ts and the contributions and biological...
28.
Bagdonaite I, Norden R, Joshi H, Dabelsteen S, Nystrom K, Vakhrushev S, et al.
PLoS Pathog . 2015 Apr; 11(4):e1004784. PMID: 25830354
Glycosylation of viral envelope proteins is important for infectivity and interaction with host immunity, however, our current knowledge of the functions of glycosylation is largely limited to N-glycosylation because it...
29.
Joshi H, Gupta R
Methods Mol Biol . 2015 Mar; 1273:127-37. PMID: 25753707
This chapter runs through several online predictors enabling prediction of glycosylation sites on protein sequences. Most online methods provide in place documentation and examples, but this chapter provides a general...
30.
Hansen L, Lind-Thomsen A, Joshi H, Pedersen N, Have C, Kong Y, et al.
Glycobiology . 2014 Oct; 25(2):211-24. PMID: 25267602
Glycosylation of proteins and lipids involves over 200 known glycosyltransferases (GTs), and deleterious defects in many of the genes encoding these enzymes cause disorders collectively classified as congenital disorders of...