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Hinako M Takase

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Articles 11
Citations 219
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Recent Articles
1.
Takase H, Mishina T, Hayashi T, Yoshimura M, Kuse M, Nikaido I, et al.
PLoS One . 2024 Oct; 19(10):e0311978. PMID: 39441825
Primordial follicle activation (PFA) is a pivotal event in female reproductive biology, coordinating the transition from quiescent to growing follicles. This study employed comprehensive single-cell RNA sequencing to gain insights...
2.
Takenaka M, Takase H, Suzuki N, Saigo C, Takeuchi T, Furui T
Reprod Biol . 2024 Oct; 24(4):100959. PMID: 39405921
Chemotherapy-induced ovarian toxicity in patients with cancer significantly affects future fertility depending on the age of initiation of treatment. However, the mechanisms underlying the age-related depletion of the ovarian reserve...
3.
Mori M, Koshiguchi M, Takenouchi O, Mukose M, Takase H, Mishina T, et al.
Genes Cells . 2024 Jul; 29(10):808-819. PMID: 39044347
Mammalian oocytes undergo a long-term meiotic arrest that can last for almost the entire reproductive lifespan. This arrest occurs after DNA replication and is prolonged with age, which poses a...
4.
Uchida A, Imaimatsu K, Suzuki H, Han X, Ushioda H, Uemura M, et al.
Nat Commun . 2022 Dec; 13(1):7860. PMID: 36543770
Seminiferous tubules (STs) in the mammalian testes are connected to the rete testis (RT) via a Sertoli valve (SV). Spermatozoa produced in the STs are released into the tubular luminal...
5.
Habara O, Logan C, Kanai-Azuma M, Nusse R, Takase H
Development . 2021 Apr; 148(9). PMID: 33914868
In mammalian ovaries, immature oocytes are reserved in primordial follicles until their activation for potential ovulation. Precise control of primordial follicle activation (PFA) is essential for reproduction, but how this...
6.
Imura-Kishi K, Uchida A, Tsunekawa N, Suzuki H, Takase H, Hirate Y, et al.
Sci Rep . 2021 Jan; 11(1):1110. PMID: 33441739
In mammalian testes, undifferentiated spermatogonia (A) undergo differentiation in response to retinoic acid (RA), while their progenitor states are partially maintained by fibroblast growth factors (FGFs). Sertoli valve (SV) is...
7.
Kishi K, Uchida A, Takase H, Suzuki H, Kurohmaru M, Tsunekawa N, et al.
Reproduction . 2017 Jun; 154(2):135-143. PMID: 28559472
USP9X (ubiquitin-specific peptidase 9, X chromosome) is the mammalian orthologue of deubiquitinase fat facets that was previously shown to regulate the maintenance of the germ cell lineage partially through stabilizing...
8.
Uchida A, Kishi K, Aiyama Y, Miura K, Takase H, Suzuki H, et al.
Biochem Biophys Res Commun . 2016 Jun; 476(4):546-552. PMID: 27255992
In mouse testes, spermatogonial stem cells (SSCs), a subpopulation of GFRα1 (GDNF family receptor-α1)-positive spermatogonia, are widely distributed along the convoluted seminiferous tubules. The proliferation and differentiation of the SSCs...
9.
Hirate Y, Suzuki H, Kawasumi M, Takase H, Igarashi H, Naquet P, et al.
Sci Rep . 2016 Apr; 6:24171. PMID: 27053385
Embryonic implantation comprises a dynamic and complicated series of events, which takes place only when the maternal uterine endometrium is in a receptive state. Blastocysts reaching the uterus communicate with...
10.
Takase H, Nusse R
Proc Natl Acad Sci U S A . 2016 Mar; 113(11):E1489-97. PMID: 26929341
Spermatogonial stem cells (SSCs) fuel the production of male germ cells but the mechanisms behind SSC self-renewal, proliferation, and differentiation are still poorly understood. Using the Wnt target gene Axin2...