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Hideki Narumi

Explore the profile of Hideki Narumi including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 47
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Recent Articles
1.
Chon H, Kanamori S, Hibino K, Nagahara T, Suzuki T, Ohara K, et al.
Bioorg Med Chem Lett . 2022 Dec; 80:129117. PMID: 36584791
The conserved N-linked glycan at the Fc domain of recombinant monoclonal antibodies is an attractive target for site-specific payload conjugation for preparation of homogenous antibody-drug conjugates (ADCs). Here, we report...
2.
Yokokawa H, Shinohara M, Teraoka Y, Imamura M, Nakamura N, Watanabe N, et al.
PLoS One . 2022 Sep; 17(9):e0274283. PMID: 36137152
In recent years, new direct-acting antivirals for hepatitis C virus (HCV) have been approved, but hepatitis C continues to pose a threat to human health. It is important to develop...
3.
Kondo T, Yamamoto T, Okayama K, Narumi H, Inoue H
Sci Rep . 2022 Mar; 12(1):2690. PMID: 35236875
Microbial flora is investigated to be related with neuropathological conditions in Alzheimer's disease (AD), and is attracting attention as a drug discovery resource. However, the relevance between the soil microbiota...
4.
Tsuge M, Uchida T, Hiraga N, Kan H, Makokha G, Abe-Chayama H, et al.
Antimicrob Agents Chemother . 2017 Apr; 61(6). PMID: 28373196
Although nucleot(s)ide analogues and pegylated interferon alpha 2a (PEG-IFN-α2a) can suppress hepatitis B virus (HBV) replication, it is difficult to achieve complete HBV elimination from hepatocytes. A novel site-specific pegylated...
5.
Iwamura T, Narumi H, Suzuki T, Yanai H, Mori K, Yamashita K, et al.
Cancer Sci . 2017 Jan; 108(4):581-589. PMID: 28129467
Malignant ascites manifests as an end-stage event during the progression of a number of cancers and lacks a generally accepted standard therapy. Interferon-β (IFN-β) has been used to treat several...
6.
Ishii M, Koyama A, Iseki H, Narumi H, Yokoyama N, Kojima N
Int Immunopharmacol . 2010 Jun; 10(9):1041-6. PMID: 20584630
Administration of oligomannose-coated liposomes (OMLs) in mice can induce Th1 immune responses against antigens entrapped in the OMLs. In the present study, we investigated the anti-allergic effect of treatment with...
7.
Sone S, Izawa A, Narumi H, Kajita A, Tanabe J, Taguchi F
Hepatol Res . 2007 Feb; 37(2):121-6. PMID: 17300707
Aim: To determine the differences in efficacy between therapy using IFN-beta and ribavirin, and using IFN-alpha and ribavirin. Methods: We studied the effect of combination therapy consisting of IFN-beta and...
8.
Teramura Y, Okamura Y, Takeoka S, Tsuchiyama H, Narumi H, Kainoh M, et al.
Biochem Biophys Res Commun . 2003 Jun; 306(1):256-60. PMID: 12788097
The recombinant fragment of the platelet membrane glycoprotein Ia/IIa (rGPIa/IIa) was conjugated to the polymerized albumin particles (polyAlb) with the average diameter of 180 nm. The intravenous administration of rGPIa/IIa-polyAlb...