Herbert Y Meltzer
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Explore the profile of Herbert Y Meltzer including associated specialties, affiliations and a list of published articles.
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299
Citations
8035
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Recent Articles
11.
Rajagopal L, Huang M, He W, Ryan C, Elzokaky A, Banerjee P, et al.
Behav Brain Res
. 2022 Jun;
432:113964.
PMID: 35718230
Rapastinel, a positive N-methyl-D-aspartate receptor (NMDAR) modulator with rapid-acting antidepressant properties, rescues memory deficits in rodents. We have previously reported that a single intravenous dose of rapastinel, significantly, but only...
12.
Orr M, Cao A, Wang C, Gaisin A, Csakai A, Friswold A, et al.
ACS Med Chem Lett
. 2022 Apr;
13(4):648-657.
PMID: 35450369
The serotonin 5-HT receptors are important pharmaceutical targets involved in signaling pathways underlying various neurological, psychiatric, and cardiac functions and dysfunctions. As such, numerous ligands for the investigation of these...
13.
Li J, Yoshikawa A, Alliey-Rodriguez N, Meltzer H
Transl Psychiatry
. 2022 Mar;
12(1):92.
PMID: 35250027
We examined whether common variants from the extended major histocompatibility complex (xMHC) region contribute to the response to antipsychotic drugs (APDs) in patients with schizophrenia with persistent psychosis. Subjects participated...
14.
Martinez Agulleiro L, de Filippis R, Rosson S, Patil B, Prizgint L, Talasazan N, et al.
Aust N Z J Psychiatry
. 2021 Nov;
56(10):1287-1294.
PMID: 34784772
Objective: Self-reports or patient-reported outcome measures are seldom used in psychosis due to concerns about the ability of patients to accurately report their symptomatology, particularly in cases of low awareness...
15.
Meltzer H, Gadaleta E
Focus (Am Psychiatr Publ)
. 2021 Sep;
19(1):3-13.
PMID: 34483761
The beliefs that antipsychotic drugs (APDs) are 1) effective to treat delusions and hallucinations (positive symptoms), 2) that typical and atypical APDs differ in ability to cause extrapyramidal side effects,...
16.
Gibbons R, Chattopadhyay I, Meltzer H, Kane J, Guinart D
Schizophr Res
. 2021 Apr;
245:116-121.
PMID: 33836922
We develop a two-stage diagnostic classification system for psychotic disorders using an extremely randomized trees machine learning algorithm. Item bank was developed from clinician-rated items drawn from an inpatient and...
17.
Kim H, Rajagopal L, Meltzer H, Martina M
Sci Adv
. 2021 Apr;
7(14).
PMID: 33789887
Cognitive impairment in schizophrenia (CIAS) is the most critical predictor of functional outcome. Limited understanding of the cellular mechanisms of CIAS hampers development of more effective treatments. We found that...
18.
Kim Y, Kong Q, Yamamoto S, Kuramoto K, Huang M, Wang N, et al.
Sci Adv
. 2021 Feb;
7(8).
PMID: 33608268
Drug abuse is a foremost public health problem. Cocaine is a widely abused drug worldwide that produces various reward-related behaviors. The mechanisms that underlie cocaine-induced disorders are unresolved, and effective...
19.
Massey B, Jayathilake K, Meltzer H
Front Microbiol
. 2020 Sep;
11:2079.
PMID: 32983056
Co-infection with additional pathogens is a well-known feature of pandemics. We determined the prevalence and type of a wide variety of respiratory pathogens in 12,075 United States subjects tested for...
20.
Lu J, Tiwari A, Freeman N, Zai G, De Luca V, Muller D, et al.
Pharmacogenomics
. 2020 Sep;
21(15):1065-1072.
PMID: 32969762
Tardive dyskinesia (TD) is an iatrogenic involuntary movement disorder occurring after extended antipsychotic use with unclear pathogenesis. is a liver enzyme involved in antipsychotic metabolism and a well-studied gene candidate...