James L Kennedy
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Explore the profile of James L Kennedy including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Zai G, Zai C, Goncalves V, Wigg K, Lochner C, Stein D, et al.
Prog Neuropsychopharmacol Biol Psychiatry
. 2025 Mar;
138:111315.
PMID: 40054571
Few pharmacogenetic studies on the use of genetic variations to predict antidepressant response in obsessive-compulsive disorder (OCD) have been published. This study expanded on the limited literature on single nucleotide...
2.
OConnell K, Koromina M, van der Veen T, Boltz T, David F, Yang J, et al.
Nature
. 2025 Jan;
PMID: 39843750
Bipolar disorder is a leading contributor to the global burden of disease. Despite high heritability (60-80%), the majority of the underlying genetic determinants remain unknown. We analysed data from participants...
3.
Zai C, Dimick M, Young L, Kennedy J, Goldstein B
J Affect Disord
. 2025 Jan;
375:44-48.
PMID: 39800071
Purpose: The risk of suicide among individuals with bipolar disorder (BD) is among the highest of all psychiatric disorders. The etiology of suicidality is complex and multifactorial, with genetic factors...
4.
Elsheikh S, Marshe V, Men X, Islam F, Goncalves V, Pare G, et al.
Pharmacogenomics J
. 2024 Nov;
24(6):38.
PMID: 39578436
Late-life depression (LLD) is often accompanied by medical comorbidities such as psychiatric disorders and cardiovascular diseases, posing challenges to antidepressant treatment. Recent studies highlighted significant associations between treatment-resistant depression (TRD)...
5.
Ye W, Zhang R, Hosang G, Fabbri C, King N, Strauss J, et al.
Psychiatr Genet
. 2024 Nov;
34(6):124-133.
PMID: 39527116
Background: Previous studies have shown that genes in brain development pathways may have important roles in affecting risk of suicidal behaviors, with our previous meta-analysis supporting a role of the...
6.
Rajji T, Bowie C, Herrmann N, Pollock B, Lanctot K, Kumar S, et al.
JAMA Psychiatry
. 2024 Oct;
82(1):12-21.
PMID: 39476073
Importance: Older adults with major depressive disorder (MDD) or mild cognitive impairment (MCI) are at high risk for cognitive decline. Objective: To assess the efficacy of cognitive remediation (CR) plus...
7.
Choi J, Beroncal E, Chernega T, Brooks H, Kennedy J, Fisher C, et al.
Transl Psychiatry
. 2024 Oct;
14(1):457.
PMID: 39468012
Mild cognitive impairment (MCI) is a prodromal stage in aging to possible progression to Alzheimer's disease and related dementia (ADRD), where co-occurrence of major depressive disorder (MDD) accelerates the progression....
8.
Akbarian N, Ebrahimi M, Dos Santos F, Afjeh S, Abdelhack M, Sanches M, et al.
Behav Sci (Basel)
. 2024 Oct;
14(10).
PMID: 39457748
Cognitive decline is a public health concern affecting about 50 million individuals worldwide. Neuroticism, defined as the trait disposition to experience intense and frequent negative emotions, has been associated with...
9.
Teymouri K, Ebrahimi M, Chen C, Sriretnakumar V, Mohiuddin A, Tiwari A, et al.
Psychiatry Res
. 2024 Sep;
342:116202.
PMID: 39342786
The complement component 4 (C4) gene, codes for two isotypes, C4A and C4B, and can exist in long or short forms (C4L and C4S). The C4AL variant has been associated...
10.
Zack M, Behzadi A, Biback C, Chugani B, DiGiacomo D, Fang T, et al.
Pharmacol Biochem Behav
. 2024 Sep;
245():173865.
PMID: 39236810
Understanding the relationship between empathy, subjective effects of addictive reinforcers and dopamine function in people with gambling disorder (PGD) vs. healthy controls (HCs) may inform GD treatment. The current investigation...