» Authors » Henri J Vial

Henri J Vial

Explore the profile of Henri J Vial including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 40
Citations 735
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Berger O, Ortial S, Wein S, Denoyelle S, Bressolle F, Durand T, et al.
Bioorg Med Chem Lett . 2019 Jul; 29(16):2203-2207. PMID: 31255483
Plasmodium falciparum is responsible for most of the cases of malaria and its resistance to established antimalarial drugs is a major issue. Thus, new chemotherapies are needed to fight the...
2.
Wein S, Ghezal S, Bure C, Maynadier M, Perigaud C, Vial H, et al.
J Lipid Res . 2018 Jun; 59(8):1461-1471. PMID: 29853527
The malaria parasite, , develops and multiplies in the human erythrocyte. It needs to synthesize considerable amounts of phospholipids (PLs), principally phosphatidylcholine (PC), phosphatidylethanolamine (PE), and phosphatidylserine (PS). Several metabolic...
3.
Wein S, Taudon N, Maynadier M, Van Ba C, Margout D, Bordat Y, et al.
Antimicrob Agents Chemother . 2017 Jun; 61(8). PMID: 28607017
Albitiazolium is the lead compound of bisthiazolium choline analogues and exerts powerful and antimalarial activities. Here we provide new insight into the fate of albitiazolium in mice and how it...
4.
Pegoraro S, Duffey M, Otto T, Wang Y, Rosemann R, Baumgartner R, et al.
Nat Commun . 2017 Apr; 8:15273. PMID: 28383016
No abstract available.
5.
Pegoraro S, Duffey M, Otto T, Wang Y, Rosemann R, Baumgartner R, et al.
Nat Commun . 2017 Feb; 8:14193. PMID: 28139658
Severe malaria is a life-threatening complication of an infection with the protozoan parasite Plasmodium falciparum, which requires immediate treatment. Safety and efficacy concerns with currently used drugs accentuate the need...
6.
Penarete-Vargas D, Boisson A, Urbach S, Chantelauze H, Peyrottes S, Fraisse L, et al.
PLoS One . 2014 Dec; 9(12):e113918. PMID: 25470252
Plasmodium falciparum is responsible for severe malaria which is one of the most prevalent and deadly infectious diseases in the world. The antimalarial therapeutic arsenal is hampered by the onset...
7.
Wein S, Van Ba C, Maynadier M, Bordat Y, Perez J, Peyrottes S, et al.
Antimicrob Agents Chemother . 2014 Jul; 58(9):5519-27. PMID: 25001307
Bis-thiazolium salts constitute a new class of antihematozoan drugs that inhibit parasite phosphatidylcholine biosynthesis. They specifically accumulate in Plasmodium- and Babesia-infected red blood cells (IRBC). Here, we provide new insight...
8.
Sen P, Vial H, Radulescu O
BMC Syst Biol . 2013 Nov; 7:123. PMID: 24209716
Background: Plasmodium is the causal parasite of malaria, infectious disease responsible for the death of up to one million people each year. Glycerophospholipid and consequently membrane biosynthesis are essential for...
9.
Pasini E, van den Ierssel D, Vial H, Kocken C
Malar J . 2013 Jun; 12:190. PMID: 23758788
Background: Malaria is a major health and socio-economical problem in tropical and sub-tropical areas of the world. Several methodologies have been used to assess parasite viability during the adaption of...
10.
Macedo J, Schmidt R, Maser P, Rentsch D, Vial H, Sigel E, et al.
Mol Biochem Parasitol . 2013 Jun; 190(1):16-22. PMID: 23747277
Choline is an essential nutrient for eukaryotic cells, where it is used as precursor for the synthesis of choline-containing phospholipids, such as phosphatidylcholine (PC). According to published data, Trypanosoma brucei...