Henri G A M van Luenen
Overview
Explore the profile of Henri G A M van Luenen including associated specialties, affiliations and a list of published articles.
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11
Citations
256
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Recent Articles
1.
Kivinen K, van Luenen H, Alcalay M, Bock C, Dodzian J, Hoskova K, et al.
EMBO Rep
. 2022 Aug;
23(9):e55734.
PMID: 35997112
Core facilities play a central role in the life sciences by generating data and ensuring quality standards. Their contributions to research should be appropriately acknowledged or cited in research papers.
2.
Bentires-Alj M, Rajan A, van Harten W, van Luenen H, Kubicek S, Andersen J, et al.
Trends Mol Med
. 2015 Aug;
21(9):525-7.
PMID: 26254816
Translational research leaves no-one indifferent and everyone expects a particular benefit. We as EU-LIFE (www.eu-life.eu), an alliance of 13 research institutes in European life sciences, would like to share our...
3.
Genest P, Baugh L, Taipale A, Zhao W, Jan S, van Luenen H, et al.
Nucleic Acids Res
. 2015 Feb;
43(4):2102-15.
PMID: 25662217
Base J (β-D-glucosyl-hydroxymethyluracil) replaces 1% of T in the Leishmania genome and is only found in telomeric repeats (99%) and in regions where transcription starts and stops. This highly restricted...
4.
van Luenen H, Farris C, Jan S, Genest P, Tripathi P, Velds A, et al.
Cell
. 2012 Sep;
150(5):909-21.
PMID: 22939620
Some Ts in nuclear DNA of trypanosomes and Leishmania are hydroxylated and glucosylated to yield base J (β-D-glucosyl-hydroxymethyluracil). In Leishmania, about 99% of J is located in telomeric repeats. We...
5.
van Harten W, van Bokhorst L, van Luenen H
Mol Oncol
. 2009 Oct;
4(1):12-8.
PMID: 19819199
International competition forces fundamental research organizations to assess their relative performance. We present a benchmark tool for scientific research organizations where, contrary to existing models, the group leader is placed...
6.
Yu Z, Genest P, Riet B, Sweeney K, DiPaolo C, Kieft R, et al.
Nucleic Acids Res
. 2007 Mar;
35(7):2107-15.
PMID: 17389644
Trypanosomatids contain an unusual DNA base J (beta-d-glucosylhydroxymethyluracil), which replaces a fraction of thymine in telomeric and other DNA repeats. To determine the function of base J, we have searched...
7.
Telomeric localization of the modified DNA base J in the genome of the protozoan parasite Leishmania
Genest P, Riet B, Cijsouw T, van Luenen H, Borst P
Nucleic Acids Res
. 2007 Mar;
35(7):2116-24.
PMID: 17329373
Base J or beta-d-glucosylhydroxymethyluracil is a DNA modification replacing a fraction of thymine in the nuclear DNA of kinetoplastid parasites and of Euglena. J is located in the telomeric sequences...
8.
van Luenen H, Kieft R, Mussmann R, Engstler M, Riet B, Borst P
Mol Microbiol
. 2005 Sep;
58(1):151-65.
PMID: 16164555
In its mammalian host, Trypanosoma brucei covers its iron requirements by receptor-mediated uptake of host transferrin (Tf). The Tf-receptor (Tf-R) is a heterodimeric membrane protein encoded by expression site-associated gene...
9.
Bentin Toaldo C, Kieft R, Dirks-Mulder A, Sabatini R, van Luenen H, Borst P
Mol Biochem Parasitol
. 2005 Jun;
143(1):111-5.
PMID: 15935489
No abstract available.
10.
Formation of linear inverted repeat amplicons following targeting of an essential gene in Leishmania
Genest P, Riet B, Dumas C, Papadopoulou B, van Luenen H, Borst P
Nucleic Acids Res
. 2005 Mar;
33(5):1699-709.
PMID: 15781496
Attempts to inactivate an essential gene in the protozoan parasite Leishmania have often led to the generation of extra copies of the wild-type alleles of the gene. In experiments with...