Hellevi Peltoketo
Overview
Explore the profile of Hellevi Peltoketo including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
21
Citations
432
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Tuppurainen H, Laurila N, Natynki M, Eshraghi L, Tervasmaki A, Erichsen L, et al.
Cell Mol Life Sci
. 2024 Apr;
81(1):173.
PMID: 38597967
Heterozygous mutations in any of three major genes, BRCA1, BRCA2 and PALB2, are associated with high-risk hereditary breast cancer susceptibility frequently seen as familial disease clustering. PALB2 is a key...
2.
Devarajan R, Izzi V, Peltoketo H, Rask G, Kauppila S, Vaisanen M, et al.
J Clin Invest
. 2023 Jul;
133(18).
PMID: 37498672
The tumor extracellular matrix (ECM) critically regulates cancer progression and treatment response. Expression of the basement membrane component collagen XVIII (ColXVIII) is induced in solid tumors, but its involvement in...
3.
Sachsenweger J, Jansche R, Merk T, Heitmeir B, Deniz M, Faust U, et al.
Cell Death Dis
. 2023 May;
14(5):328.
PMID: 37198153
It has been well-established that mutations in BRCA1 and BRCA2, compromising functions in DNA double-strand break repair (DSBR), confer hereditary breast and ovarian cancer risk. Importantly, mutations in these genes...
4.
Jonas K, Rivero Muller A, Oduwole O, Peltoketo H, Huhtaniemi I
Endocrinology
. 2021 Feb;
162(5).
PMID: 33605422
Mouse models with altered gonadotropin functions have provided invaluable insight into the functions of these hormones/receptors. Here we describe the repurposing of the infertile and hypogonadal luteinizing hormone receptor (LHR)...
5.
Bose M, Sachsenweger J, Laurila N, Parplys A, Willmann J, Jungwirth J, et al.
Hum Mol Genet
. 2019 Oct;
28(24):4148-4160.
PMID: 31630195
Whilst heterozygous germline mutations in the ABRAXAS1 gene have been associated with a hereditary predisposition to breast cancer, their effect on promoting tumourigenesis at the cellular level has not been...
6.
Tervasmaki A, Mantere T, Eshraghi L, Laurila N, Tuppurainen H, Ronkainen V, et al.
Int J Cancer
. 2019 Feb;
145(8):2070-2081.
PMID: 30809794
Strong inherited predisposition to breast cancer is estimated to cause about 5-10% of all breast cancer cases. As the known susceptibility genes, such as BRCA1 and BRCA2, explain only a...
7.
Oduwole O, Peltoketo H, Huhtaniemi I
Front Endocrinol (Lausanne)
. 2019 Jan;
9:763.
PMID: 30619093
Spermatogenesis is a concerted sequence of events during maturation of spermatogonia into spermatozoa. The process involves differential gene-expression and cell-cell interplay regulated by the key endocrine stimuli, i.e., follicle-stimulating hormone...
8.
Oduwole O, Peltoketo H, Poliandri A, Vengadabady L, Chrusciel M, Doroszko M, et al.
J Clin Invest
. 2018 Mar;
128(5):1787-1792.
PMID: 29584617
Spermatogenesis is regulated by the 2 pituitary gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This process is considered impossible without the absolute requirement of LH-stimulated testicular testosterone (T) production....
9.
Jonas K, Oduwole O, Peltoketo H, Rulli S, Huhtaniemi I
Reproduction
. 2014 Jul;
148(4):R63-70.
PMID: 25030890
The advent of technologies to genetically manipulate the mouse genome has revolutionised research approaches, providing a unique platform to study the causality of reproductive disorders in vivo. With the relative...
10.
Grynberg M, Peltoketo H, Christin-Maitre S, Poulain M, Bouchard P, Fanchin R
J Clin Endocrinol Metab
. 2013 Aug;
98(11):4493-8.
PMID: 23956344
Context: The association of primary amenorrhea, gonadotropin levels at menopausal range, and normal antral follicle endowment is a rare clinical condition that suggests unresponsiveness of antral follicles to FSH. This...