Hellevi Peltoketo
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Explore the profile of Hellevi Peltoketo including associated specialties, affiliations and a list of published articles.
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21
Citations
432
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Recent Articles
11.
Nagirnaja L, Venclovas C, Rull K, Jonas K, Peltoketo H, Christiansen O, et al.
Mol Hum Reprod
. 2012 May;
18(8):379-90.
PMID: 22554618
Heterodimeric hCG is one of the key hormones determining early pregnancy success. We have previously identified rare missense mutations in hCGβ genes with potential pathophysiological importance. The present study assessed...
12.
Peltoketo H, Zhang F, Rulli S
Rev Endocr Metab Disord
. 2011 Apr;
12(4):245-58.
PMID: 21484328
During the last two decades a large number of genetically modified mouse lines with altered gonadotropin action have been generated. These mouse lines fall into three categories: the lack-of-function mice,...
13.
Peltoketo H, Strauss L, Karjalainen R, Zhang M, Stamp G, Segaloff D, et al.
Endocrinology
. 2010 Feb;
151(4):1872-83.
PMID: 20172968
Strong gain-of-function mutations have not been identified in humans in the FSH receptor (FSHR), whereas such mutations are common among many other G protein-coupled receptors. In order to predict consequences...
14.
Shan J, Jokela T, Peltoketo H, Vainio S
Genesis
. 2009 Oct;
47(11):782-8.
PMID: 19830824
The Wnt family member Wnt4 is critical for the development of several organs, including the kidney, gonad, and adrenal, mammary, and pituitary glands. To study its potential postnatal functions, we...
15.
Bernichtein S, Peltoketo H, Huhtaniemi I
Mol Cell Endocrinol
. 2008 Nov;
300(1-2):164-8.
PMID: 19007852
Gonadectomy induces in certain inbred stains of mice adrenal hyperplasia and tumorigenesis, originating from the putative subcapsular stem/progenitor cell layer. This response is apparently triggered by the elevated post-gonadectomy levels...
16.
Itaranta P, Chi L, Seppanen T, Niku M, Tuukkanen J, Peltoketo H, et al.
Dev Biol
. 2006 Mar;
293(2):473-83.
PMID: 16546160
Wnt-4, a member of the Wnt family of secreted signaling molecules, is essential for nephrogenesis, but its expression in the presumptive medulla suggests additional developmental roles in kidney organogenesis. We...
17.
Heikkila M, Prunskaite R, Naillat F, Itaranta P, Vuoristo J, Leppaluoto J, et al.
Endocrinology
. 2005 Jun;
146(9):4016-23.
PMID: 15932923
Wnt-4 signaling has been implicated in female development, because its absence leads to partial female to male sex reversal in the mouse. Instead of Mullerian ducts, Wnt-4-deficient females have Wolffian...
18.
Peltoketo H, Allinen M, Vuosku J, Kujala S, Lundan T, Salminen A, et al.
Cancer Lett
. 2004 Aug;
213(1):83-90.
PMID: 15312687
Wnt4 is needed for correct development of several tissues in the mouse, and WNT4 is found here to be expressed in a temporal manner in human embryonic tissues. In addition,...
19.
Torn S, Nokelainen P, Kurkela R, Pulkka A, Menjivar M, Ghosh S, et al.
Biochem Biophys Res Commun
. 2003 May;
305(1):37-45.
PMID: 12732193
17beta-Hydroxysteroid dehydrogenases (17HSDs) have a central role in the regulation of the biological activity of sex steroid hormones. There is increasing evidence that in addition to their importance in gonads,...
20.
Lin Y, Zhang S, Tuukkanen J, Peltoketo H, Pihlajaniemi T, Vainio S
Int J Dev Biol
. 2003 Mar;
47(1):3-13.
PMID: 12653247
The mechanisms by which the branching of epithelial tissue occurs and is regulated to generate different organ structures are not well understood. In this work, image analyses of the organ...