Helen M Marriott
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Explore the profile of Helen M Marriott including associated specialties, affiliations and a list of published articles.
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Articles
41
Citations
2010
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0
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Recent Articles
11.
Gill S, Marriott H, Suvarna S, Peachell P
Eur J Pharmacol
. 2016 Nov;
793:49-55.
PMID: 27832943
The principal mechanism by which bronchodilator β-adrenoceptor agonists act is to relax airways smooth muscle although they may also be anti-inflammatory. However, the extent of anti-inflammatory activity and the cell...
12.
Gill S, Yao Y, Kay L, Bewley M, Marriott H, Peachell P
Br J Pharmacol
. 2016 Jul;
173(21):3099-3109.
PMID: 27460634
Background And Purpose: PGE inhibits cytokine generation from human lung macrophages. However, the EP receptor that mediates this beneficial anti-inflammatory effect of PGE has not been defined. The aim of...
13.
Jubrail J, Morris P, Bewley M, Stoneham S, Johnston S, Foster S, et al.
Cell Microbiol
. 2015 Aug;
18(1):80-96.
PMID: 26248337
Macrophages are critical effectors of the early innate response to bacteria in tissues. Phagocytosis and killing of bacteria are interrelated functions essential for bacterial clearance but the rate-limiting step when...
14.
Masca N, Hensor E, Cornelius V, Buffa F, Marriott H, Eales J, et al.
Elife
. 2015 May;
4.
PMID: 25951517
Lack of reproducibility is an ongoing problem in some areas of the biomedical sciences. Poor experimental design and a failure to engage with experienced statisticians at key stages in the...
15.
Bewley M, Naughton M, Preston J, Mitchell A, Holmes A, Marriott H, et al.
mBio
. 2014 Oct;
5(5):e01710-14.
PMID: 25293758
Intracellular killing of Streptococcus pneumoniae is complemented by induction of macrophage apoptosis. Here, we show that the toxin pneumolysin (PLY) contributes both to lysosomal/phagolysosomal membrane permeabilization (LMP), an upstream event...
16.
Thompson A, Elks P, Marriott H, Eamsamarng S, Higgins K, Lewis A, et al.
Blood
. 2013 Nov;
123(3):366-76.
PMID: 24196071
Neutrophil lifespan and function are regulated by hypoxia via components of the hypoxia inducible factor (HIF)/von Hippel Lindau/hydroxylase pathway, including specific roles for HIF-1α and prolyl hydroxylase-3. HIF-2α has both...
17.
Bazaz R, Marriott H, Francis S, Dockrell D
J Infect
. 2012 Oct;
66(1):1-17.
PMID: 23046969
Cardiovascular disease has emerged as the leading cause of mortality worldwide. Acute coronary syndromes occur as a result of thrombotic complications at the site of atherosclerotic plaques, often following rupture...
18.
Musa M, Wilson K, Sun L, Mulay A, Bingle L, Marriott H, et al.
Cell Tissue Res
. 2012 Sep;
350(3):455-64.
PMID: 22986921
Despite being initially identified in mice, little is known about the sites of production of members of the BPI fold (BPIF) containing (PLUNC) family of putative innate defence proteins in...
19.
Daigneault M, I de Silva T, Bewley M, Preston J, Marriott H, Mitchell A, et al.
PLoS Pathog
. 2012 Jul;
8(7):e1002814.
PMID: 22829769
Monocytes and T-cells are critical to the host response to acute bacterial infection but monocytes are primarily viewed as amplifying the inflammatory signal. The mechanisms of cell death regulating T-cell...
20.
Marriott H, Daigneault M, Thompson A, Walmsley S, Gill S, Witcher D, et al.
Thorax
. 2012 Jun;
67(11):985-92.
PMID: 22735687
Background: Therapeutic strategies to modulate the host response to bacterial pneumonia are needed to improve outcomes during community-acquired pneumonia. This study used mice with impaired Fas signalling to examine susceptibility...