Helen M Marriott
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Explore the profile of Helen M Marriott including associated specialties, affiliations and a list of published articles.
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Articles
41
Citations
2010
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0
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Recent Articles
1.
Bazaz R, Marriott H, Wright C, Chamberlain J, West L, Gelsthorpe C, et al.
Front Cell Infect Microbiol
. 2023 Apr;
13:1090550.
PMID: 37033482
Introduction: Despite epidemiological associations between community acquired pneumonia (CAP) and myocardial infarction, mechanisms that modify cardiovascular disease during CAP are not well defined. In particular, largely due to a lack...
2.
Herman K, Wright C, Marriott H, McCaughran S, Bowden K, Collins M, et al.
Front Immunol
. 2022 Aug;
13:956991.
PMID: 35967296
Dysregulated neutrophilic inflammation can be highly destructive in chronic inflammatory diseases due to prolonged neutrophil lifespan and continual release of histotoxic mediators in inflamed tissues. Therapeutic induction of neutrophil apoptosis,...
3.
Marsh E, Prestwich E, Williams L, Hart A, Muir C, Parker L, et al.
Front Cell Infect Microbiol
. 2020 Sep;
10:456.
PMID: 32984077
Exposure to respiratory pathogens is a leading cause of exacerbations of airway diseases such as asthma and chronic obstructive pulmonary disease (COPD). Pellino-1 is an E3 ubiquitin ligase known to...
4.
Fenaroli F, Robertson J, Scarpa E, Gouveia V, Di Guglielmo C, De Pace C, et al.
ACS Nano
. 2020 Jun;
14(7):8287-8298.
PMID: 32515944
Mononuclear phagocytes such as monocytes, tissue-specific macrophages, and dendritic cells are primary actors in both innate and adaptive immunity. These professional phagocytes can be parasitized by intracellular bacteria, turning them...
5.
Hughes B, Burton C, Reese A, Jabeen M, Wright C, Willis J, et al.
Front Immunol
. 2019 Aug;
10:1721.
PMID: 31417543
Non-typeable (NTHi) is a frequent cause of lower respiratory tract infection in people with chronic obstructive pulmonary disease (COPD). Pellino proteins are a family of E3 ubiquitin ligases that are...
6.
Preston J, Bewley M, Marriott H, Houghton A, Mohasin M, Jubrail J, et al.
Am J Respir Crit Care Med
. 2019 Jan;
200(1):84-97.
PMID: 30649895
Antimicrobial resistance challenges therapy of pneumonia. Enhancing macrophage microbicidal responses would combat this problem but is limited by our understanding of how alveolar macrophages (AMs) kill bacteria. To define the...
7.
Braithwaite A, Marriott H, Lawrie A
Front Med (Lausanne)
. 2018 Aug;
5:212.
PMID: 30101145
The tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) is a widely expressed cytokine that can bind five different receptors. TRAIL has been of particular interest for its proposed ability to selectively...
8.
Collini P, Bewley M, Mohasin M, Marriott H, Miller R, Geretti A, et al.
Am J Respir Crit Care Med
. 2018 Jan;
197(12):1604-1615.
PMID: 29365279
Rationale: People living with HIV are at significantly increased risk of invasive pneumococcal disease, despite long-term antiretroviral therapy (ART). The mechanism explaining this observation remains undefined. Objectives: To determine if...
9.
Sadiku P, Willson J, Dickinson R, Murphy F, Harris A, Lewis A, et al.
J Clin Invest
. 2017 Aug;
127(9):3407-3420.
PMID: 28805660
Fully activated innate immune cells are required for effective responses to infection, but their prompt deactivation and removal are essential for limiting tissue damage. Here, we have identified a critical...
10.
Bewley M, Preston J, Mohasin M, Marriott H, Budd R, Swales J, et al.
Am J Respir Crit Care Med
. 2017 May;
196(7):845-855.
PMID: 28557543
Rationale: Chronic obstructive pulmonary disease (COPD) is characterized by impaired clearance of pulmonary bacteria. Objectives: The effect of COPD on alveolar macrophage (AM) microbicidal responses was investigated. Methods: AMs were...