Helen Farr
Overview
Explore the profile of Helen Farr including associated specialties, affiliations and a list of published articles.
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10
Citations
737
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Recent Articles
1.
Abeywickrema M, Vachova H, Farr H, Mohr T, Wheeler R, Lai D, et al.
Mol Microbiol
. 2019 Jul;
112(3):1024-1040.
PMID: 31286583
Differentiation of Trypanosoma brucei, a flagellated protozoan parasite, between life cycle stages typically occurs through an asymmetric cell division process, producing two morphologically distinct daughter cells. Conversely, proliferative cell divisions...
2.
Golubchik T, Batty E, Miller R, Farr H, Young B, Larner-Svensson H, et al.
PLoS One
. 2013 May;
8(5):e61319.
PMID: 23658690
Background: Staphylococcus aureus is a major cause of healthcare associated mortality, but like many important bacterial pathogens, it is a common constituent of the normal human body flora. Around a...
3.
Farr H, Gull K
Cytoskeleton (Hoboken)
. 2012 Oct;
69(11):931-41.
PMID: 23027706
Cytokinesis is a crucial step in the cell division cycle whereby the cell membrane and underlying cortex is remodelled and drawn together to create two new daughter cells. While in...
4.
Tiengwe C, Marcello L, Farr H, Dickens N, Kelly S, Swiderski M, et al.
Cell Rep
. 2012 Jul;
2(1):185-97.
PMID: 22840408
Identification of replication initiation sites, termed origins, is a crucial step in understanding genome transmission in any organism. Transcription of the Trypanosoma brucei genome is highly unusual, with each chromosome...
5.
Tiengwe C, Marcello L, Farr H, Gadelha C, Burchmore R, Barry J, et al.
PLoS One
. 2012 Mar;
7(3):e32674.
PMID: 22412905
DNA replication initiates by formation of a pre-replication complex on sequences termed origins. In eukaryotes, the pre-replication complex is composed of the Origin Recognition Complex (ORC), Cdc6 and the MCM...
6.
Farr H, Gull K
Cell Motil Cytoskeleton
. 2008 Nov;
66(1):24-35.
PMID: 19009637
Eukaryotic cilia and flagella are highly conserved structures composed of a canonical 9+2 microtubule axoneme. Several recent proteomic studies of cilia and flagella have been published, including a proteome of...
7.
Dawe H, Shaw M, Farr H, Gull K
BMC Biol
. 2007 Aug;
5:33.
PMID: 17683645
Background: Impairment of cilia and flagella function underlies a growing number of human genetic diseases. Mutations in hydin in hy3 mice cause lethal communicating hydrocephalus with early onset. Hydin was...
8.
Dawe H, Farr H, Gull K
J Cell Sci
. 2006 Dec;
120(Pt 1):7-15.
PMID: 17182899
Cilia, either motile or immotile, exist on most cells in the human body. There are several different mechanisms of ciliogenesis, which enable the production of many kinds of cilia and...
9.
Broadhead R, Dawe H, Farr H, Griffiths S, Hart S, Portman N, et al.
Nature
. 2006 Mar;
440(7081):224-7.
PMID: 16525475
The 9 + 2 microtubule axoneme of flagella and cilia represents one of the most iconic structures built by eukaryotic cells and organisms. Both unity and diversity are present among...
10.
Dawe H, Farr H, Portman N, Shaw M, Gull K
J Cell Sci
. 2005 Nov;
118(Pt 23):5421-30.
PMID: 16278296
Eukaryotic cilia and flagella are highly conserved structures composed of a canonical 9+2 microtubule axoneme. Comparative genomics of flagellated and non-flagellated eukaryotes provides one way to identify new putative flagellar...