Calvin Tiengwe
Overview
Explore the profile of Calvin Tiengwe including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
17
Citations
351
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Carbajo C, Han X, Savur B, Upadhyaya A, Taha F, Tinti M, et al.
Open Biol
. 2025 Feb;
15(2):240334.
PMID: 39999874
Kinetoplastid parasites cause diseases that threaten human and animal health. To survive transitions between vertebrate hosts and insect vectors, these parasites rely on precise regulation of gene expression to adapt...
2.
Carbajo C, Han X, Savur B, Upadhyaya A, Taha F, Tinti M, et al.
bioRxiv
. 2024 Nov;
PMID: 39554005
Kinetoplastid parasites cause diseases that threaten human and animal health. To survive transitions between vertebrate hosts and insect vectors, these parasites rely on precise regulation of gene expression to adapt...
3.
Duncan S, Carbajo C, Nagar R, Zhong Q, Breen C, Ferguson M, et al.
PLoS Pathog
. 2024 Jun;
20(6):e1012333.
PMID: 38935804
The bloodstream form of Trypanosoma brucei expresses large poly-N-acetyllactosamine (pNAL) chains on complex N-glycans of a subset of glycoproteins. It has been hypothesised that pNAL may be required for receptor-mediated...
4.
Budzak J, Goodwin I, Tiengwe C, Rudenko G
Mol Biochem Parasitol
. 2023 Nov;
256:111598.
PMID: 37923299
Visualisation of genomic loci by microscopy is essential for understanding nuclear organisation, particularly at the single cell level. One powerful technique for studying the positioning of genomic loci is through...
5.
Wincott C, Sritharan G, Benns H, May D, Gilabert-Carbajo C, Bunyan M, et al.
Cell Rep Methods
. 2022 Sep;
2(8):100274.
PMID: 36046624
Cellular barcoding techniques are powerful tools to understand microbial pathogenesis. However, barcoding strategies have not been broadly applied to protozoan parasites, which have unique genomic structures and virulence strategies compared...
6.
Carbajo C, Cornell L, Madbouly Y, Lai Z, Yates P, Tinti M, et al.
PLoS Pathog
. 2021 Jun;
17(6):e1009696.
PMID: 34161395
Iron is an essential regulatory signal for virulence factors in many pathogens. Mammals and bloodstream form (BSF) Trypanosoma brucei obtain iron by receptor-mediated endocytosis of transferrin bound to receptors (TfR)...
7.
Koeller C, Tiengwe C, Schwartz K, Bangs J
J Biol Chem
. 2020 Jan;
295(8):2227-2238.
PMID: 31932305
The transferrin receptor (TfR) of the bloodstream form (BSF) of is a heterodimer comprising glycosylphosphatidylinositol (GPI)-anchored expression site-associated gene 6 (ESAG6 or E6) and soluble ESAG7. Mature E6 has five...
8.
Tiengwe C
mSphere
. 2019 Sep;
4(5).
PMID: 31484744
Calvin Tiengwe works on posttranscriptional gene regulation and iron homeostasis in the parasitic protozoan In this article, he reflects on how the paper "Comprehensive identification of RNA-protein interactions in any...
9.
Tiengwe C, Koeller C, Bangs J
Mol Biol Cell
. 2018 Aug;
29(20):2397-2409.
PMID: 30091673
Misfolded secretory proteins are retained by endoplasmic reticulum quality control (ERQC) and degraded in the proteasome by ER-associated degradation (ERAD). However, in yeast and mammals, misfolded glycosylphosphatidylinositol (GPI)-anchored proteins are...
10.
Tiengwe C, Bush P, Bangs J
PLoS Pathog
. 2017 May;
13(5):e1006366.
PMID: 28459879
Bloodstream-form African trypanosomes encode two structurally related glycosylphosphatidylinositol (GPI)-anchored proteins that are critical virulence factors, variant surface glycoprotein (VSG) for antigenic variation and transferrin receptor (TfR) for iron acquisition. Both...