Hazel Y Stevens
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Explore the profile of Hazel Y Stevens including associated specialties, affiliations and a list of published articles.
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44
Citations
929
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Recent Articles
1.
Chatterjee P, Stevens H, Kippner L, Bowles-Welch A, Drissi H, Mautner K, et al.
iScience
. 2024 Sep;
27(9):110827.
PMID: 39310769
Knee osteoarthritis (OA) is a significant medical and economic burden. To understand systemic immune effects, we performed deep exploration of bone marrow aspirate concentrates (BMACs) from knee-OA patients via single-cell...
2.
Stevens H, Jimenez A, Wang B, Li Y, Selvam S, Bowles-Welch A
Bio Protoc
. 2024 Jun;
14(6):e4957.
PMID: 38841292
Stem cell-based therapies have evolved to become a key component of regenerative medicine approaches to human pathologies. Exogenous stem cell transplantation takes advantage of the potential of stem cells to...
3.
Li Y, Stevens H, Sivaraman S, Porter L, Hoffman A, Gibb S, et al.
Bio Protoc
. 2023 Dec;
13(24):e4900.
PMID: 38156031
Streamlined procedures for processing and cryopreservation of cell therapies using good laboratory practices are integral to biomanufacturing process development and clinical applications. The protocol herein begins with the preparation of...
4.
Lin A, Reece D, Thote T, Sridaran S, Stevens H, Willett N, et al.
Front Bioeng Biotechnol
. 2023 Sep;
11:1224141.
PMID: 37744252
Micronized dehydrated human amnion/chorion membrane (mdHACM) has reduced short term post-traumatic osteoarthritis (PTOA) progression in rats when delivered 24 h after medial meniscal transection (MMT) and is being investigated for...
5.
Bowles-Welch A, Jimenez A, Stevens H, Frey Rubio D, Kippner L, Yeago C, et al.
Bone Rep
. 2023 Jul;
18:101656.
PMID: 37425195
Bone is a complex tissue capable of natural repair to injury, however, the healing process is often impaired by the untoward effects of trauma, defects, and disease. Thus, therapeutic modalities,...
6.
Salazar-Noratto G, Nations C, Stevens H, Xu M, Gaynard S, Dooley C, et al.
Stem Cells Transl Med
. 2023 May;
12(5):293-306.
PMID: 37184892
Juvenile osteochondritis dissecans (JOCD) is a pediatric disease, which begins with an osteonecrotic lesion in the secondary ossification center which, over time, results in the separation of the necrotic fragment...
7.
Medrano-Trochez C, Chatterjee P, Pradhan P, Stevens H, Ogle M, Botchwey E, et al.
Stem Cell Res Ther
. 2021 Nov;
12(1):565.
PMID: 34736534
Background: Human Mesenchymal stromal cells (hMSCs) from various tissue sources are widely investigated in clinical trials. These MSCs are often administered to patients immediately after thawing the cryopreserved product (out-of-thaw),...
8.
Stevens H, Bowles A, Yeago C, Roy K
Front Cell Dev Biol
. 2020 Dec;
8:600160.
PMID: 33363157
Mesenchymal stromal cells (MSCs) have been widely investigated for regenerative medicine applications, from treating various inflammatory diseases as a cell therapy to generating engineered tissue constructs. Numerous studies have evaluated...
9.
Allen A, Zimmermann J, Burnsed O, Yakubovich D, Stevens H, Gazit Z, et al.
J Mater Chem B
. 2020 Apr;
4(20):3594-3607.
PMID: 32263389
While mesenchymal stem cell (MSC)-based strategies for critically-sized bone defect repair hold promise, poor cell survival in vivo remains a significant barrier to the translation of these therapeutics. One method...
10.
The Effects of Age and Dose on Gene Expression and Segmental Bone Defect Repair After BMP-2 Delivery
Cheng A, Krishnan L, Tran L, Stevens H, Xia B, Lee N, et al.
JBMR Plus
. 2019 Mar;
3(2):e10068.
PMID: 30828685
Age is a well-known influential factor in bone healing, with younger patients generally healing bone fractures more rapidly and suffering fewer complications compared with older patients. Yet the impact age...