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Harvey Sage

Explore the profile of Harvey Sage including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 271
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Recent Articles
1.
Reardon P, Sage H, Dennison S, Martin J, Donald B, Alam S, et al.
Proc Natl Acad Sci U S A . 2014 Jan; 111(4):1391-6. PMID: 24474763
The membrane proximal external region (MPER) of HIV-1 glycoprotein (gp) 41 is involved in viral-host cell membrane fusion. It contains short amino acid sequences that are binding sites for the...
2.
Capp C, Qian Y, Sage H, Huber H, Hsieh T
J Biol Chem . 2010 Oct; 285(51):39637-45. PMID: 20929866
Reverse gyrase reanneals denatured DNA and induces positive supercoils in DNA, an activity that is critical for life at very high temperatures. Positive supercoiling occurs by a poorly understood mechanism...
3.
Augustus A, Sage H, Spicer L
Biochemistry . 2010 Mar; 49(15):3289-95. PMID: 20196619
We have used analytical ultracentrifugation to characterize the binding of the methionine repressor protein, MetJ, to synthetic oligonucleotides containing zero to five specific recognition sites, called metboxes. For all lengths...
4.
Sontag C, Sage H, Erickson H
PLoS One . 2009 Sep; 4(9):e7253. PMID: 19787042
Background: BtubA and BtubB are two tubulin-like genes found in the bacterium Prosthecobacter. Our work and a previous crystal structure suggest that BtubB corresponds to alpha-tubulin and BtubA to beta-tubulin....
5.
Moss M, Bomar M, Liu Q, Sage H, Dempsey P, Lenhart P, et al.
J Biol Chem . 2007 Sep; 282(49):35712-21. PMID: 17895248
ADAM10 is a disintegrin metalloproteinase that processes amyloid precursor protein and ErbB ligands and is involved in the shedding of many type I and type II single membrane-spanning proteins. Like...
6.
Li M, Phatnani H, Guan Z, Sage H, Greenleaf A, Zhou P
Proc Natl Acad Sci U S A . 2005 Nov; 102(49):17636-41. PMID: 16314571
The phosphorylation state of the C-terminal repeat domain (CTD) of the largest subunit of RNA polymerase II changes as polymerase transcribes a gene, and the distinct forms of the phospho-CTD...
7.
Chu H, Yun M, Anderson D, Sage H, Park H, Endow S
EMBO J . 2005 Aug; 24(18):3214-23. PMID: 16107877
Kar3, a kinesin-14 motor of Saccharomyces cerevisiae required for mitosis and karyogamy, reportedly interacts with Cik1, a nonmotor protein, via its central, predicted coiled coil. Despite this, neither Kar3 nor...
8.
Bjornson K, Blackwell L, Sage H, Baitinger C, Allen D, Modrich P
J Biol Chem . 2003 Jun; 278(36):34667-73. PMID: 12829697
Analytical equilibrium ultracentrifugation indicates that Escherichia coli MutS exists as an equilibrating mixture of dimers and tetramers. The association constant for the dimer-to-tetramer transition is 2.1 x 10(7) M-1, indicating...
9.
Hu T, Sage H, Hsieh T
J Biol Chem . 2002 Feb; 277(8):5944-51. PMID: 11850431
We have prepared full-length Drosophila and human topoisomerase II and truncation constructs containing the amino-terminal ATPase domain, and we have analyzed their biochemical properties. The ATPase activity of the truncation...