Haochen Jiang
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Explore the profile of Haochen Jiang including associated specialties, affiliations and a list of published articles.
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22
Citations
220
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Recent Articles
1.
Wang W, Xing J, Zhang X, Liu H, Liu X, Jiang H, et al.
Elife
. 2025 Feb;
13.
PMID: 40009443
Existence of cilia in the last eukaryotic common ancestor raises a fundamental question in biology: how the transcriptional regulation of ciliogenesis has evolved? One conceptual answer to this question is...
2.
Jiang H, Althobaiti S, Pinkerton B, Fu X, Jia Z, Foster K, et al.
Animal Model Exp Med
. 2025 Feb;
PMID: 39917824
Background: Reliable animal models are crucial to drug development for focal segmental glomerulosclerosis (FSGS), a rare kidney disease. Variability in success rates in literature and significant ethical concerns with animal...
3.
Jiang H, Fu X, Zhao G, Du X, Georgesen C, Thiele G, et al.
Mol Pharm
. 2024 Sep;
21(10):4995-5004.
PMID: 39224912
Psoriasis is a chronic immune-mediated inflammatory skin disease, affecting ∼ 3% of the US population. Although multiple new systemic therapies have been introduced for the treatment of psoriatic skin disease,...
4.
Wei X, Zhao G, Chen N, Xu X, Jiang H, Tran D, et al.
Nanomedicine
. 2024 Aug;
62:102782.
PMID: 39179013
The relief of joint pain is one of the main objectives in the clinical management of arthritis. Although significant strides have been made in improving management of rheumatoid and related...
5.
Xu C, Wei Z, Lv L, Dong X, Xia W, Xing J, et al.
Biochem Biophys Res Commun
. 2024 Jul;
727:150317.
PMID: 38959733
Abnormalities in osteoclastic generation or activity disrupt bone homeostasis and are highly involved in many pathologic bone-related diseases, including rheumatoid arthritis, osteopetrosis, and osteoporosis. Control of osteoclast-mediated bone resorption is...
6.
Xu C, Wei Z, Dong X, Xing J, Meng X, Qiu Y, et al.
Biochem Pharmacol
. 2024 Jun;
226:116391.
PMID: 38914317
Inhibition of excessive osteoclastic activity is an efficient therapeutic strategy for many bone diseases induced by increased bone resorption, such as osteoporosis. BMS-582949, a clinical p38α inhibitor, is a promising...
7.
Hu J, Zheng S, Hua M, Ding M, Hu Z, Jiang H
Biochem Biophys Res Commun
. 2024 May;
716:149998.
PMID: 38692012
The equilibrium between the hypertrophic growth of existing adipocytes and adipogenesis is vital in managing metabolic stability in white adipocytes when faced with overnutrition. Adipogenesis has been established as a...
8.
Tan P, Wang S, Li G, Wang H, Zhao Z, Jiang H, et al.
J Org Chem
. 2024 Apr;
89(9):6405-6415.
PMID: 38603543
An oxidative cascade iodocyclization of 1,7- or 1,8-dienes has been realized under mild conditions. By employing I as an iodine source, this protocol provides a concise and efficient approach to...
9.
Chen N, Wei X, Zhao G, Jia Z, Fu X, Jiang H, et al.
Nanomedicine
. 2024 Jan;
57:102735.
PMID: 38295913
In this study, we aimed to assess the analgesic efficacy of a thermoresponsive polymeric dexamethasone (Dex) prodrug (ProGel-Dex) in a mouse model of osteoarthritis (OA). At 12 weeks post model...
10.
Zhuang S, He M, Feng J, Peng S, Jiang H, Li Y, et al.
Small Methods
. 2023 Sep;
7(11):e2300848.
PMID: 37681531
Near-infrared (NIR) photothermal manipulation has emerged as a promising and noninvasive technology for neuroscience research and disease therapy for its deep tissue penetration. NIR stimulated techniques have been used to...