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Steven R Goldring

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Articles 103
Citations 6820
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Recent Articles
1.
Ziemian S, Antoinette A, Witkowski A, Otero M, Goldring S, Goldring M, et al.
Osteoarthritis Cartilage . 2025 Feb; PMID: 40020990
Objective: While physiological loads maintain cartilage health, both joint overload and abnormal joint mechanical loading contribute to osteoarthritis (OA) development. Here, we examined the role of abnormal mechanical loading on...
2.
Jiang H, Fu X, Zhao G, Du X, Georgesen C, Thiele G, et al.
Mol Pharm . 2024 Sep; 21(10):4995-5004. PMID: 39224912
Psoriasis is a chronic immune-mediated inflammatory skin disease, affecting ∼ 3% of the US population. Although multiple new systemic therapies have been introduced for the treatment of psoriatic skin disease,...
3.
Wei X, Zhao G, Chen N, Xu X, Jiang H, Tran D, et al.
Nanomedicine . 2024 Aug; 62:102782. PMID: 39179013
The relief of joint pain is one of the main objectives in the clinical management of arthritis. Although significant strides have been made in improving management of rheumatoid and related...
4.
Antoinette A, Ziemian S, Brown A, Hudson E, Chlebek C, Wright T, et al.
Sci Adv . 2024 Apr; 10(16):eadk8402. PMID: 38640238
Osteoarthritis (OA) treatment is limited by the lack of effective nonsurgical interventions to slow disease progression. Here, we examined the contributions of the subchondral bone properties to OA development. We...
5.
Jia Z, Wei X, Chen N, Xu X, Zhao G, Fu X, et al.
Mol Pharm . 2024 Feb; 21(4):1838-1847. PMID: 38413029
The extensive use of opioids for chronic pain management has contributed significantly to the current opioid epidemic. While many alternative nonopioid analgesics are available, opioids remain the most potent analgesics...
6.
Chen N, Wei X, Zhao G, Jia Z, Fu X, Jiang H, et al.
Nanomedicine . 2024 Jan; 57:102735. PMID: 38295913
In this study, we aimed to assess the analgesic efficacy of a thermoresponsive polymeric dexamethasone (Dex) prodrug (ProGel-Dex) in a mouse model of osteoarthritis (OA). At 12 weeks post model...
7.
Ayobami O, Goldring S, Goldring M, Wright T, van der Meulen M
Bone Rep . 2022 Jul; 17:101602. PMID: 35899096
Objective: Clinical evidence suggests that abnormal mechanical forces play a major role in the initiation and progression of osteoarthritis (OA). However, few studies have examined the mechanical environment that leads...
8.
Olivotto E, Trisolino G, Belluzzi E, Lazzaro A, Strazzari A, Pozzuoli A, et al.
J Clin Med . 2022 Jul; 11(15). PMID: 35893418
Background: The aim of the study was to examine the relationship among patients' characteristics, intraoperative pathology and pre/post-operative symptoms in a cohort of patients undergoing arthroscopic partial meniscectomy for symptomatic...
9.
Zhao Z, Jiang H, Xu X, Jia Z, Ren R, Foster K, et al.
Nanomedicine . 2022 Jun; 44:102579. PMID: 35768036
Due to their potent immunosuppressive and anti-inflammatory effects, glucocorticoids (GCs) are the most widely used medications in treating lupus nephritis (LN). Long-term use of GCs, however, is associated with numerous...
10.
Olivotto E, Belluzzi E, Pozzuoli A, Cigolotti A, Scioni M, Goldring S, et al.
Int J Mol Sci . 2022 Apr; 23(7). PMID: 35409262
The menisci exert a prominent role in joint stabilization and in the distribution of mechanical loading. Meniscal damage is associated with increased risk of knee OA. The aim of this...