Hansjorg Schwertz
Overview
Explore the profile of Hansjorg Schwertz including associated specialties, affiliations and a list of published articles.
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Articles
47
Citations
1617
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Recent Articles
1.
Boettger P, Schwertz H, Platsch H, Mueller-Werdan U, Werdan K, Buerke M
Proteomics Clin Appl
. 2025 Feb;
:e202400066.
PMID: 39993432
Introduction: Percutaneous transluminal coronary angioplasty (PTCA) is an effective procedure to decrease the severity of stenotic coronary atherosclerotic lesions. However, its long-term success is limited by the formation of restenosis...
2.
Bottger P, Grosser T, Ibe W, Boissel J, Lindemann S, Werdan K, et al.
J Vasc Res
. 2025 Feb;
:1-19.
PMID: 39907989
Vascular smooth muscle cell proliferation and vascular homeostasis is thought to be regulated by nitric oxide and prostaglandins. We examined the effect of exogenous linsidomine, a NO releasing compound, in...
3.
Seylani A, Galsinh A, Tasoula A, I A, Camera A, Calleja-Agius J, et al.
Nat Commun
. 2024 Jun;
15(1):4774.
PMID: 38862473
Mounting ambitions and capabilities for public and private, non-government sector crewed space exploration bring with them an increasingly diverse set of space travelers, raising new and nontrivial ethical, legal, and...
4.
Freitag M, Schwertz H
Int J Mol Sci
. 2022 Dec;
23(23).
PMID: 36499021
Platelets (PLTs) are anucleate and considered incapable of nuclear functions. Contrastingly, nuclear proteins were detected in human PLTs. For most of these proteins, it is unclear if nuclear or alternatively...
5.
Campbell R, Manne B, Banerjee M, Middleton E, Ajanel A, Schwertz H, et al.
J Clin Invest
. 2022 Oct;
132(23).
PMID: 36194487
Platelets and megakaryocytes are critical players in immune responses. Recent reports suggest infection and inflammation alter the megakaryocyte and platelet transcriptome to induce altered platelet reactivity. We determined whether nonviral...
6.
Schwertz H, Middleton E
Thromb Res
. 2022 Sep;
231:170-181.
PMID: 36058760
Autophagy, the continuous recycling of intracellular building blocks, molecules, and organelles is necessary to preserve cellular function and homeostasis. In this context, it was demonstrated that autophagy plays an important...
7.
Schwertz H, Rowley J, Portier I, Middleton E, Tolley N, Campbell R, et al.
Autophagy
. 2021 Oct;
18(7):1534-1550.
PMID: 34689707
Platelets mediate central aspects of host responses during sepsis, an acute profoundly systemic inflammatory response due to infection. Macroautophagy/autophagy, which mediates critical aspects of cellular responses during inflammatory conditions, is...
8.
Wende A, Schell J, Ha C, Pepin M, Khalimonchuk O, Schwertz H, et al.
Diabetes
. 2020 May;
69(10):2094-2111.
PMID: 32366681
Cardiac glucose uptake and oxidation are reduced in diabetes despite hyperglycemia. Mitochondrial dysfunction contributes to heart failure in diabetes. It is unclear whether these changes are adaptive or maladaptive. To...
9.
Rondina M, Voora D, Simon L, Schwertz H, Harper J, Lee O, et al.
Circ Res
. 2019 Dec;
126(4):501-516.
PMID: 31852401
Rationale: Longitudinal studies are required to distinguish within versus between-individual variation and repeatability of gene expression. They are uniquely positioned to decipher genetic signal from environmental noise, with potential application...
10.
Middleton E, Rowley J, Campbell R, Grissom C, Brown S, Beesley S, et al.
Blood
. 2019 Aug;
134(12):911-923.
PMID: 31366617
There is increasing recognition that platelets have a functional role in the pathophysiology of sepsis, though this role has not been precisely defined. Whether sepsis alters the human platelet transcriptome...