Hans C Oettgen
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Explore the profile of Hans C Oettgen including associated specialties, affiliations and a list of published articles.
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68
Citations
2895
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Recent Articles
1.
El Ansari Y, Kanagaratham C, Furiness K, Furiness K, Brodeur K, Brodeur K, et al.
Mucosal Immunol
. 2025 Jan;
PMID: 39824503
Immunoglobulin A (IgA), the most abundantly produced antibody at mucosal surfaces, is thought to play key roles in immune responses to respiratory and enteric pathogens and in the regulation of...
2.
Furiness K, El Ansari Y, Oettgen H, Kanagaratham C
Front Allergy
. 2024 Jun;
5:1389669.
PMID: 38919913
Food allergy, a group of adverse immune responses to normally innocuous food protein antigens, is an increasingly prevalent public health issue. The most common form is IgE-mediated food allergy in...
3.
Nguyen A, Habiballah S, LaBere B, Day-Lewis M, Elkins M, Al-Musa A, et al.
J Allergy Clin Immunol Pract
. 2023 Aug;
11(11):3391-3399.e3.
PMID: 37544429
Background: Debates on the allocation of medical resources during the coronavirus disease 2019 (COVID-19) pandemic revealed the need for a better understanding of immunological risk. Studies highlighted variable clinical outcomes...
4.
Nguyen A, Habiballah S, LaBere B, Day-Lewis M, Elkins M, Al-Musa A, et al.
medRxiv
. 2023 Jun;
PMID: 37333367
Background: Debates on the allocation of medical resources during the COVID-19 pandemic revealed the need for a better understanding of immunologic risk. Studies highlighted variable clinical outcomes of SARS-CoV-2 infections...
5.
Kanagaratham C, Derakhshan T, El Ansari Y, Furiness K, Hollers E, Keldsen M, et al.
J Allergy Clin Immunol
. 2023 Apr;
152(2):453-468.
PMID: 37030590
Background: IgE-induced mast cell (MC) degranulation can be inhibited by IgG antibodies, signaling via FcγRIIb, but the effects of IgG on IgE-induced MC transcription are unknown. Objective: We sought to...
6.
Oettgen H
J Allergy Clin Immunol
. 2022 Nov;
151(1):21-25.
PMID: 36328809
Mast cells are distributed throughout the gastrointestinal tract and function as the main effector cells of IgE-mediated allergic reactions to foods. Allergen-induced cross-linking of IgE antibodies bound to high-affinity IgE...
7.
El Ansari Y, Kanagaratham C, Burton O, Santos J, Hollister B, Lewis O, et al.
Front Immunol
. 2022 Jul;
13:881655.
PMID: 35865546
Mast cells and basophils have long been implicated in the pathogenesis of IgE-mediated hypersensitivity reactions. They express the high-affinity IgE receptor, FcϵRI, on their surface. Antigen-induced crosslinking of IgE antibodies...
8.
Chen G, Shrock E, Li M, Spergel J, Nadeau K, Pongracic J, et al.
Cell Rep Med
. 2021 Nov;
2(10):100410.
PMID: 34755130
Peanut allergy can result in life-threatening reactions and is a major public health concern. Oral immunotherapy (OIT) induces desensitization to food allergens through administration of increasing amounts of allergen. To...
9.
Manohar M, Dunham D, Gupta S, Yan Z, Zhang W, Minnicozzi S, et al.
Allergy
. 2021 Mar;
76(9):2809-2826.
PMID: 33782956
Background: Multifood oral immunotherapy (mOIT) with adjunctive anti-IgE (omalizumab, XOLAIR ) treatment affords safe, effective, and rapid desensitization to multiple foods, although the specific immune mechanisms mediating this desensitization remain...
10.
El Ansari Y, Kanagaratham C, Oettgen H
Yale J Biol Med
. 2020 Dec;
93(5):711-718.
PMID: 33380933
Mast cells are a critical first line of defense against endogenous and environmental threats. Their participation in innate immunity is well characterized; activation of toll like receptors as well as...