Hans C Oettgen
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Explore the profile of Hans C Oettgen including associated specialties, affiliations and a list of published articles.
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68
Citations
2895
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Recent Articles
11.
Kanagaratham C, El Ansari Y, Lewis O, Oettgen H
Front Immunol
. 2020 Dec;
11:603050.
PMID: 33362785
Food allergy is a major health issue, affecting the lives of 8% of U.S. children and their families. There is an urgent need to identify the environmental and endogenous signals...
12.
Turner J, Stephen-Victor E, Wang S, Noval Rivas M, Abdel-Gadir A, Harb H, et al.
Immunity
. 2020 Dec;
53(6):1331-1332.
PMID: 33326768
No abstract available.
13.
Phipatanakul W, Mauger D, Guilbert T, Bacharier L, Durrani S, Jackson D, et al.
Contemp Clin Trials
. 2020 Nov;
100:106228.
PMID: 33242697
Asthma remains one of the most important challenges to pediatric public health in the US. A large majority of children with persistent and chronic asthma demonstrate aeroallergen sensitization, which remains...
14.
El Ansari Y, Kanagaratham C, Lewis O, Oettgen H
Adv Immunol
. 2020 Nov;
148:93-153.
PMID: 33190734
Mast cells and IgE are most familiar as the effectors of type I hypersensitivity reactions including anaphylaxis. It is becoming clear however that this pair has important immunomodulatory effects on...
15.
Turner J, Stephen-Victor E, Wang S, Noval Rivas M, Abdel-Gadir A, Harb H, et al.
Immunity
. 2020 Oct;
53(6):1202-1214.e6.
PMID: 33086036
The mechanisms by which regulatory T (Treg) cells differentially control allergic and autoimmune responses remain unclear. We show that Treg cells in food allergy (FA) had decreased expression of transforming...
16.
Kanagaratham C, El Ansari Y, Sallis B, Hollister B, Lewis O, Minnicozzi S, et al.
J Allergy Clin Immunol
. 2020 Mar;
146(4):884-893.e5.
PMID: 32194041
Background: Patients with eosinophilic esophagitis have increased numbers of mucosal mast cells. Administration of the proton pump inhibitor omeprazole can reduce both esophageal mast cell and eosinophil numbers and attenuate...
17.
Stranks A, Minnicozzi S, Miller S, Burton O, Logsdon S, Spergel J, et al.
Ann Allergy Asthma Immunol
. 2018 Nov;
122(2):213-215.
PMID: 30404033
No abstract available.
18.
Burton O, Epp A, Fanny M, Miller S, Stranks A, Teague J, et al.
Front Immunol
. 2018 Jun;
9:1244.
PMID: 29928276
Immediate hypersensitivity reactions are induced by the interaction of allergens with specific IgE antibodies bound FcεRI to mast cells and basophils. While these specific IgE antibodies are needed to trigger...
19.
Renz H, Allen K, Sicherer S, Sampson H, Lack G, Beyer K, et al.
Nat Rev Dis Primers
. 2018 Jan;
4:17098.
PMID: 29300005
Food allergies manifest in a variety of clinical conditions within the gastrointestinal tract, skin and lungs, with the most dramatic and sometimes fatal manifestation being anaphylactic shock. Major progress has...
20.
Burton O, Tamayo J, Stranks A, Koleoglou K, Oettgen H
J Allergy Clin Immunol
. 2017 May;
141(1):189-201.e3.
PMID: 28479335
Background: Patients with food allergy produce high-titer IgE antibodies that bind to mast cells through FcεRI and trigger immediate hypersensitivity reactions on antigen encounter. Food-specific IgG antibodies arise in the...