Hans-Heinrich Hoffmann
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Explore the profile of Hans-Heinrich Hoffmann including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Meyer C, Garzia A, Miller M, Huggins D, Myers R, Hoffmann H, et al.
Nature
. 2024 Dec;
637(8048):1178-1185.
PMID: 39663451
Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The rapid development of highly effective vaccines against SARS-CoV-2 has altered the trajectory of the pandemic,...
2.
Lercher A, Cheong J, Bale M, Jiang C, Hoffmann H, Ashbrook A, et al.
Immunity
. 2024 Oct;
57(11):2530-2546.e13.
PMID: 39353439
Pathogen encounter can result in epigenetic remodeling that shapes disease caused by heterologous pathogens. Here, we examined innate immune memory in the context of commonly circulating respiratory viruses. Single-cell analyses...
3.
Pham M, Hoffmann H, Kurtti T, Chana R, Garcia-Cruz O, Aliabadi S, et al.
iScience
. 2024 Aug;
27(8):110468.
PMID: 39139404
is an important vector of many pathogens, including the causative agent of Lyme disease. The gene function studies in and other ticks are hampered by the lack of genetic tools,...
4.
Cervantes Rincon T, Kapoor T, Keeffe J, Simonelli L, Hoffmann H, Agudelo M, et al.
Cell Rep
. 2024 May;
43(6):114298.
PMID: 38819991
Flaviviruses such as dengue virus (DENV), Zika virus (ZIKV), and yellow fever virus (YFV) are spread by mosquitoes and cause human disease and mortality in tropical areas. In contrast, Powassan...
5.
Zang T, Kuffour E, Baharani V, Canis M, Schmidt F, Da Silva J, et al.
Proc Natl Acad Sci U S A
. 2023 Dec;
120(51):e2317367120.
PMID: 38096415
Vaccination will likely be a key component of strategies to curtail or prevent future sarbecovirus pandemics and to reduce the prevalence of infection and disease by future SARS-CoV-2 variants. A...
6.
Lercher A, Cheong J, Jiang C, Hoffmann H, Ashbrook A, Yin Y, et al.
bioRxiv
. 2023 Dec;
PMID: 38076887
Pathogen encounter results in long-lasting epigenetic imprinting that shapes diseases caused by heterologous pathogens. The breadth of this innate immune memory is of particular interest in the context of respiratory...
7.
Pham M, Hoffmann H, Kurtti T, Chana R, Garcia-Cruz O, Aliabadi S, et al.
bioRxiv
. 2023 Dec;
PMID: 38076872
is an important vector of many pathogens, including the causative agent of Lyme disease, tick-borne encephalitis, and anaplasmosis. The study of gene function in and other ticks has been hampered...
8.
Cheshenko N, Bonanno J, Hoffmann H, Jangra R, Chandran K, Rice C, et al.
Commun Biol
. 2023 Aug;
6(1):833.
PMID: 37563206
No abstract available.
9.
Cheung A, Yip E, Ashbrook A, Goonawardane N, Quirk C, Rice C, et al.
Vaccines (Basel)
. 2023 Mar;
11(3).
PMID: 36992196
Powassan virus (POWV) is an emerging tick-borne virus and cause of lethal encephalitis in humans. The lack of treatment or prevention strategies for POWV disease underscores the need for an...
10.
de Carvalho R, Ersching J, Barbulescu A, Hobbs A, Castro T, Mesin L, et al.
Cell
. 2022 Dec;
186(1):131-146.e13.
PMID: 36565697
Germinal centers (GCs) form in secondary lymphoid organs in response to infection and immunization and are the source of affinity-matured B cells. The duration of GC reactions spans a wide...