Theodora Hatziioannou
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Explore the profile of Theodora Hatziioannou including associated specialties, affiliations and a list of published articles.
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125
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13271
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Recent Articles
1.
Fan C, Keeffe J, Malecek K, Cohen A, West Jr A, West A, et al.
bioRxiv
. 2025 Jan;
PMID: 39803445
Therapeutic monoclonal antibodies (mAbs) against SARS-CoV-2 become obsolete as spike substitutions reduce antibody binding. To induce antibodies against conserved receptor-binding domain (RBD) regions for protection against SARS-CoV-2 variants of concern...
2.
Zhang F, Schmidt F, Muecksch F, Wang Z, Gazumyan A, Nussenzweig M, et al.
mBio
. 2024 Jan;
15(2):e0167223.
PMID: 38193662
The glycosylation of viral envelope proteins can play important roles in virus biology and immune evasion. The spike (S) glycoprotein of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) includes 22 N-linked...
3.
Sankhala R, Lal K, Jensen J, Dussupt V, Mendez-Rivera L, Bai H, et al.
Nat Commun
. 2024 Jan;
15(1):200.
PMID: 38172512
The repeat emergence of SARS-CoV-2 variants of concern (VoC) with decreased susceptibility to vaccine-elicited antibodies highlights the need to develop next-generation vaccine candidates that confer broad protection. Here we describe...
4.
Zang T, Kuffour E, Baharani V, Canis M, Schmidt F, Da Silva J, et al.
Proc Natl Acad Sci U S A
. 2023 Dec;
120(51):e2317367120.
PMID: 38096415
Vaccination will likely be a key component of strategies to curtail or prevent future sarbecovirus pandemics and to reduce the prevalence of infection and disease by future SARS-CoV-2 variants. A...
5.
Swanstrom A, Gorelick R, Welker J, Schmidt F, Lu B, Wang K, et al.
EBioMedicine
. 2023 Aug;
95:104764.
PMID: 37625266
Background: Long-acting subcutaneous lenacapavir (LEN), a first-in-class HIV capsid inhibitor approved by the US FDA for the treatment of multidrug-resistant HIV-1 with twice yearly dosing, is under investigation for HIV-1...
6.
Murphy E, Guzman-Cardozo C, Sukhu A, Parks D, Prabhu M, Mohammed I, et al.
Nat Commun
. 2023 Aug;
14(1):4598.
PMID: 37563124
The effects of heterogeneous infection, vaccination and boosting histories prior to and during pregnancy have not been extensively studied and are likely important for protection of neonates. We measure levels...
7.
Zhang F, Schmidt F, Muecksch F, Wang Z, Gazumyan A, Nussenzweig M, et al.
bioRxiv
. 2023 Jul;
PMID: 37425700
The glycosylation of viral envelope proteins can play important roles in virus biology and immune evasion. The spike (S) glycoprotein of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) includes 22 N-linked...
8.
Wang Z, Muecksch F, Raspe R, Johannsen F, Turroja M, Canis M, et al.
J Exp Med
. 2023 Jun;
220(9).
PMID: 37368240
Despite mRNA vaccination, elderly individuals remain especially vulnerable to severe consequences of SARS-CoV-2 infection. Here, we compare the memory B cell responses in a cohort of elderly and younger individuals...
9.
Zhang F, Jenkins J, de Carvalho R, Nakandakari-Higa S, Chen T, Abernathy M, et al.
Nat Microbiol
. 2023 May;
8(6):1051-1063.
PMID: 37188812
Human monoclonal antibodies (mAbs) that target the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein have been isolated from convalescent individuals and developed into therapeutics for SARS-CoV-2 infection. However,...
10.
Yang L, Van Beek M, Wang Z, Muecksch F, Canis M, Hatziioannou T, et al.
Cell Rep
. 2023 Mar;
42(4):112256.
PMID: 36952347
The Omicron variant of SARS-CoV-2 is not effectively neutralized by most antibodies elicited by two doses of mRNA vaccines, but a third dose increases anti-Omicron neutralizing antibodies. We reveal mechanisms...