Han-Shen Tae
Overview
Explore the profile of Han-Shen Tae including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
53
Citations
365
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Tae H, Hung A, Clark R, Adams D
J Biol Chem
. 2024 Nov;
301(1):108017.
PMID: 39608712
The α-conotoxins (α-Ctxs) are short, disulfide-rich peptides derived from the venom of the Conus marine snails, primarily acting as antagonists of nicotinic acetylcholine receptors (nAChRs). Specifically, α-Ctx Vc1.1, a 16-amino...
2.
Li T, Tae H, Chen S, Li X, Liang J, Pan T, et al.
J Med Chem
. 2024 Oct;
67(21):18741-18752.
PMID: 39448068
α-conotoxins (α-Ctxs), a class of disulfide-rich conopetides, are excellent drug leads due to their small size, high selectivity, and potency for specific membrane receptors and ion channels involved in pain...
3.
Li X, Zhou S, Tae H, Wang S, Li T, Cai W, et al.
J Med Chem
. 2024 Oct;
67(20):18400-18411.
PMID: 39361522
α9α10 nicotinic acetylcholine receptors (nAChRs) are a promising nonopioid analgesic target, with α9α10 nAChR antagonists showing efficacy against chemotherapy-induced hyperalgesia and allodynia. GeX-2, a potent analgesic conotoxin antagonist of α9α10...
4.
Tae H, Ortells M, Yousuf A, Xu S, Akk G, Adams D, et al.
Biochem Pharmacol
. 2024 Apr;
223:116183.
PMID: 38580167
In this study, we have investigated the pharmacological activity and structural interaction of two novel psychoplastogens, tabernanthalog (TBG) and ibogainalog (IBG) at heterologously-expressed rat (r) and human (h) nicotinic acetylcholine...
5.
Li T, Tae H, Liang J, Zhang Z, Li X, Jiang T, et al.
Mar Drugs
. 2024 Mar;
22(3).
PMID: 38535451
α-Conotoxins (α-CTxs) are structurally related peptides that antagonize nicotinic acetylcholine receptors (nAChRs), which may serve as new alternatives to opioid-based treatment for pain-related conditions. The non-natural amino acid analogues of...
6.
Li X, Tae H, Chen S, Yousuf A, Huang L, Zhang J, et al.
J Med Chem
. 2024 Jan;
67(2):971-987.
PMID: 38217860
Pain severely affects the physical and mental health of patients. The need to develop nonopioid analgesic drugs to meet medical demands is urgent. In this study, we designed a truncated...
7.
Tae H, Ortells M, Tekarli B, Manetti D, Romanelli M, McIntosh J, et al.
ACS Chem Neurosci
. 2023 Jun;
14(14):2537-2547.
PMID: 37386821
The main objective of this study was to determine the pharmacological activity and molecular mechanism of action of DM506 (3-methyl-1,2,3,4,5,6-hexahydroazepino[4,5-]indole fumarate), a novel ibogamine derivative, at different nicotinic acetylcholine receptor...
8.
Zheng M, Tae H, Xue L, Jiang T, Yu R
Mar Life Sci Technol
. 2023 Apr;
4(1):98-105.
PMID: 37073352
Supplementary Information: The online version contains supplementary material available at 10.1007/s42995-021-00108-9.
9.
Arias H, Tae H, Micheli L, Yousuf A, Manetti D, Romanelli M, et al.
Anesth Analg
. 2023 Apr;
137(3):691-701.
PMID: 37058425
Background: The primary objective of this study was to characterize the pharmacological and behavioral activity of 2 novel compounds, DM497 [(E)-3-(thiophen-2-yl)- N -(p-tolyl)acrylamide] and DM490 [(E)-3-(furan-2-yl)- N -methyl- N -(p-tolyl)acrylamide],...
10.
Tae H, Adams D
Pharmacol Res
. 2023 Mar;
191:106747.
PMID: 37001708
The pentameric nicotinic acetylcholine receptors (nAChRs) are typically classed as muscle- or neuronal-type, however, the latter has also been reported in non-neuronal cells. Given their broad distribution, nAChRs mediate numerous...