Hai-Xin Yuan
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Explore the profile of Hai-Xin Yuan including associated specialties, affiliations and a list of published articles.
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Articles
34
Citations
1468
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Recent Articles
1.
Wan B, Liu W, Xiao Y, Lv L, Li X, Lin F, et al.
Bioorg Chem
. 2025 Jan;
156:108201.
PMID: 39864374
Ferroptosis is a novel type of programmed cell death characterized by radical-driven lipid peroxidation accumulation, which is involved in various diseases, including acute organ injury and neurodegenerative disorders. Pharmacological inhibition...
2.
Zhang J, Lin F, Xiao Y, Cen S, Wan B, Li X, et al.
Eur J Med Chem
. 2024 Dec;
284():117192.
PMID: 39721290
Ferroptosis is a novel form of regulated cell death characterized by iron-dependent lipid ROS accumulation, which is associated with various diseases, including acute organ injury, neurodegenerative disorders, and cancer. Pharmacological...
3.
Cen S, Lin F, Li X, Hu Y, Liu J, Xue Z, et al.
Cell Death Discov
. 2024 Aug;
10(1):360.
PMID: 39134539
Ferroptosis is a specific form of cell death characterized by excessive accumulation of cellular lipid peroxides. Ferroptosis is closely associated with various diseases, inhibition of which may help alleviate multi-organ...
4.
Hu F, Miao Y, Yu B, Deng X, Sun R, Qian J, et al.
Am J Clin Exp Immunol
. 2024 Jul;
13(3):133-139.
PMID: 39022794
Methods: This study retrospectively analyzed data from 174 patients with cerebral infarction admitted to The Rehabilitation Department of Shanghai Fifth Rehabilitation Hospital and Shanghai First People's Hospital from June 2022...
5.
Duan K, Wang T, You J, Wang H, Wang Z, Huang Z, et al.
Immunology
. 2024 Jun;
173(2):339-359.
PMID: 38934051
Maintaining intracellular redox balance is essential for the survival, antibody secretion, and mucosal immune homeostasis of immunoglobulin A (IgA) antibody-secreting cells (ASCs). However, the relationship between mitochondrial metabolic enzymes and...
6.
Liu J, Cen S, Xue Z, Wang T, Gao Y, Zheng J, et al.
ACS Chem Biol
. 2022 Nov;
17(12):3389-3406.
PMID: 36446024
Ferroptosis is a nonapoptotic form of cell death characterized by iron-dependent lipid peroxidation and has been implicated in multiple pathological conditions. Glutathione peroxidase 4 (GPX4) plays an essential role in...
7.
Sun S, Ai Y, Duan K, Zhang J, Zhang C, Sun Y, et al.
Oncogene
. 2022 Nov;
41(50):5385-5396.
PMID: 36348011
TET2 (ten-eleven-translocation) protein is a Fe(II)- and α-ketoglutarate-dependent dioxygenase that catalyzes DNA demethylation to regulate gene expression. While TET2 gene is frequently mutated in hematological cancer, its enzymatic activity is...
8.
Li X, Zhong S, Sun Y, Huang X, Li Y, Wang L, et al.
Front Endocrinol (Lausanne)
. 2022 Nov;
13:951093.
PMID: 36329886
Background: Non-alcoholic fatty liver disease (NAFLD), a metabolic disorder that develops from non-alcoholic fatty liver (NAFL) to non-alcoholic steatohepatitis (NASH), has become an epidemic of chronic liver dysfunction worldwide. However,...
9.
Wang T, Duan K, Huang Z, Xue Z, Liang J, Dang Y, et al.
Life Sci Alliance
. 2022 Nov;
6(1).
PMID: 36319062
Ferroptosis is triggered by the breakdown of cellular iron-dependent redox homeostasis and the abnormal accumulation of lipid ROS. Cells have evolved defense mechanisms to prevent lipid ROS accumulation and ferroptosis....
10.
ALK fusion promotes metabolic reprogramming of cancer cells by transcriptionally upregulating PFKFB3
Hu M, Bao R, Lin M, Han X, Ai Y, Gao Y, et al.
Oncogene
. 2022 Sep;
41(40):4547-4559.
PMID: 36064579
Anaplastic lymphoma kinase (ALK), a receptor tyrosine kinase of the insulin receptor kinase subfamily, is activated in multiple cancer types through translocation or overexpression. Although several generations of ALK tyrosine...