Hagit Eldar-Finkelman
Overview
Explore the profile of Hagit Eldar-Finkelman including associated specialties, affiliations and a list of published articles.
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58
Citations
4568
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Recent Articles
1.
Simmons D, Alexander N, Cao G, Rippin I, Lugassy Y, Eldar-Finkelman H, et al.
Neurotherapeutics
. 2024 Nov;
22(2):e00495.
PMID: 39592326
Huntington's disease (HD) is a neurodegenerative disorder caused by a CAG repeat expansion in the HTT gene encoding a mutant huntingtin (mHtt) protein. mHtt aggregates within neurons causing degeneration primarily...
2.
Wittenstein A, Caspi M, Rippin I, Elroy-Stein O, Eldar-Finkelman H, Thoms S, et al.
PLoS Biol
. 2024 Feb;
22(2):e3002524.
PMID: 38354369
[This corrects the article DOI: 10.1371/journal.pbio.3002355.].
3.
Wittenstein A, Caspi M, Rippin I, Elroy-Stein O, Eldar-Finkelman H, Thoms S, et al.
PLoS Biol
. 2023 Nov;
21(11):e3002355.
PMID: 37943958
The introduction of premature termination codons (PTCs), as a result of splicing defects, insertions, deletions, or point mutations (also termed nonsense mutations), lead to numerous genetic diseases, ranging from rare...
4.
Farfara D, Sooliman M, Avrahami L, Royal T, Amram S, Rozenstein-Tsalkovich L, et al.
J Neuroinflammation
. 2023 Jul;
20(1):174.
PMID: 37496076
Background: Alzheimer's disease (AD) is the leading cause of dementia in the world. The pathology of AD is affiliated with the elevation of both tau (τ) and β-amyloid (Aβ) pathologies....
5.
Elkoshi N, Parikh S, Malcov-Brog H, Parikh R, Manich P, Netti F, et al.
J Invest Dermatol
. 2023 May;
143(12):2494-2506.e4.
PMID: 37236596
Skin pigmentation is paused after sun exposure; however, the mechanism behind this pausing is unknown. In this study, we found that the UVB-induced DNA repair system, led by the ataxia...
6.
Sheinboim D, Parikh S, Manich P, Markus I, Dahan S, Parikh R, et al.
Cancer Res
. 2022 Sep;
82(22):4164-4178.
PMID: 36084256
Significance: Exercise protects against cancer progression and metastasis by inducing a high nutrient demand in internal organs, indicating that reducing nutrient availability to tumor cells represents a potential strategy to...
7.
Ruiz S, Rippin I, Eldar-Finkelman H
Cells
. 2022 May;
11(10).
PMID: 35626655
Over the last decade, there has been continuous progress in our understanding of the biology of the protein kinase GSK-3 [...].
8.
Moaraf S, Rippin I, Terkel J, Eldar-Finkelman H, Barnea A
Front Physiol
. 2022 May;
13:881174.
PMID: 35574473
Glycogen synthase kinase-3 (GSK-3) is a highly conserved serine/threonine protein kinase that plays a central role in a wide variety of cellular processes, cognition and behaviour. In a previous study...
9.
Arciniegas Ruiz S, Eldar-Finkelman H
Front Mol Neurosci
. 2022 Feb;
14:792364.
PMID: 35126052
The protein kinase, GSK-3, participates in diverse biological processes and is now recognized a promising drug discovery target in treating multiple pathological conditions. Over the last decade, a range of...
10.
Rippin I, Bonder K, Joseph S, Sarsor A, Vaks L, Eldar-Finkelman H
Neurobiol Dis
. 2021 Mar;
154:105336.
PMID: 33753290
In Huntington's disease (HD), the mutant huntingtin (mHtt) accumulates as toxic aggregates in the striatum tissue, with deleterious effects on motor-coordination and cognitive functions. Reducing the levels of mHtt is...