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H Yesim Karasulu

Explore the profile of H Yesim Karasulu including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 126
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Recent Articles
1.
Diril M, Ozdokur K, Yildirim Y, Karasulu H
Pharm Dev Technol . 2023 Nov; 28(10):915-927. PMID: 37921920
Hepatocellular carcinoma (HCC), more than 800 000 cases reported annually, is the most common primary liver cancer globally. Doxorubicin hydrochloride (Dox-HCl) is a widely used chemotherapy drug for HCC, but...
2.
Gulmezoglu E, Yildiz Turkyilmaz G, Karasulu H
Drug Dev Ind Pharm . 2023 Jan; 48(12):727-736. PMID: 36594276
Antihypertensive treatment reduces the risk of cardiovascular complications in patients with high mortality with hypertension. Valsartan is highly selective antihypertensive that is rapidly absorbed after oral administration, but its oral...
3.
Birgul K, Yildirim Y, Karasulu H, Karasulu E, Ibrahim Uba A, Yelekci K, et al.
Eur J Med Chem . 2020 Sep; 208:112841. PMID: 32998089
In this study, (S)-naproxen thiosemicarbazides (3a-d), 1,2,4-triazoles (4a-c), triazole-thioether hybride compounds (5a-p) were synthesized and their structures (3a, 3d, 4a and 5a-p) were confirmed by FT-IR, H NMR,C NMR, HR-Mass...
4.
Diril M, Yildiz Turkyilmaz G, Karasulu H
Curr Drug Deliv . 2019 Aug; 16(8):768-779. PMID: 31429689
Objective: The aim of this study was to develop a new dosage form as an alternative to the classical tablet forms of atorvastatin calcium (AtrCa). The formulation strategy was to...
5.
Ilem-Ozdemir D, Ustundag-Okur N, Ay Senyigit Z, Oruc N, Asikoglu M, Ozutemiz O, et al.
Drug Deliv . 2016 Mar; 23(8):3055-3062. PMID: 26923781
Background: Aprotinin is a monomeric globular polypeptide, which derived from bovine lung tissue and theoretically attractive molecule in ameliorating the effects of acute pancreatitis. Acute pancreatitis is an inflammatory condition...
6.
Ustundag Okur N, Caglar E, Arpa M, Karasulu H
Pharm Dev Technol . 2016 Jan; 22(4):500-510. PMID: 26738443
The purpose of the current research was to prepare and evaluate the potential use of microemulsion-based hydrogel (MBH) formulations for dermal delivery of benzocaine (BZN). The pseudoternary-phase diagrams were constructed...
7.
Ustundag Okur N, Ilem Ozdemir D, Kahyaoglu S, Ay Senyigit Z, Asikoglu M, Genc L, et al.
Curr Drug Deliv . 2015 Aug; 12(6):668-79. PMID: 26306401
The object of the current study was to prepare novel microemulsion formulations of aprotinin for parenteral delivery and to compare in vitro characteristics and release behaviour of different Technetium-99m ((99m)Tc)-Aprotinin...
8.
Karasulu H, Oruc N, Ustundag-Okur N, Ilem Ozdemir D, Ay Senyigit Z, Barbet Yilmaz F, et al.
J Drug Target . 2015 Mar; 23(6):525-37. PMID: 25738992
The aim of this study was to develop aprotinin-loaded microemulsion (MA) for intravenous administration and evaluate the biodistribution and therapeutic potential of developed formulation in acute pancreatitis models in rats....
9.
Ustundag Okur N, Apaydin S, Yavasoglu N, Yavasoglu A, Karasulu H
Int J Pharm . 2011 Jul; 416(1):136-44. PMID: 21723930
The aim of this study was to evaluate the potential application of microemulsions as a transdermal drug delivery for naproxen (Np). The pseudo-ternary phase diagrams were developed for microemulsions composed...
10.
Karasulu E, Yavasoglu A, Evrensanal Z, Uyanikgil Y, Karasulu H
Drug Deliv . 2008 May; 15(4):219-25. PMID: 18446567
This study was designed to investigate the possible histological effects of different intranasal (IN) formulations of indomethacin (IND) on nasal mucosa in sheep. For this purpose, oil-in-water (O/W) emulsion (E)...