H William Schnaper
Overview
Explore the profile of H William Schnaper including associated specialties, affiliations and a list of published articles.
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48
Citations
1569
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0
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Recent Articles
1.
Sancheznieto F, Sorkness C, Attia J, Buettner K, Edelman D, Hobbs S, et al.
J Clin Transl Sci
. 2022 Feb;
6(1):e13.
PMID: 35211339
Introduction: A national survey characterized training and career development for translational researchers through Clinical and Translational Science Award (CTSA) T32/TL1 programs. This report summarizes program goals, trainee characteristics, and mentorship...
2.
McCormack W, Bredella M, Ingbar D, Jackson R, Meagher E, Morris C, et al.
J Clin Transl Sci
. 2021 May;
4(6):556-561.
PMID: 33942017
Clinical and Translational Science Award (CTSA) TL1 trainees and KL2 scholars were surveyed to determine the immediate impact of the COVID-19 pandemic on training and career development. The most negative...
3.
Schnaper H, Flynn J, Gross C, Cropp A, Dehmel B, Patel L, et al.
Pediatr Res
. 2017 Aug;
82(5):727-732.
PMID: 28853726
The conduct of clinical trials in small pediatric subspecialties such as pediatric nephrology is hampered by both clinical demands on the pediatric nephrologist and the small number of appropriate patients...
4.
Puckelwartz M, Schnaper H
Kidney Int
. 2017 Mar;
91(4):781-783.
PMID: 28314579
In this issue, Bierzynska et al. report the results of analyzing a cohort of children with steroid-resistant nephrotic syndrome (SRNS) of childhood, correlating genetic studies with clinical outcomes. This approach...
5.
Schnaper H
Adv Chronic Kidney Dis
. 2017 Mar;
24(2):107-116.
PMID: 28284376
Accumulating evidence suggests that the central locus for the progression of CKD is the renal proximal tubule. As injured tubular epithelial cells dedifferentiate in attempted repair, they stimulate inflammation and...
6.
Baumann B, Hayashida T, Liang X, Schnaper H
Kidney Int
. 2016 Aug;
90(4):797-808.
PMID: 27503806
The function of hypoxia-inducible factor-1α (HIF-1α) in chronic kidney disease is disputed. Here we report that interactions of HIF-1α with transforming growth factor-β (TGF-β) signaling may promote its fibrotic effects....
7.
Liang X, Schnaper H, Matsusaka T, Pastan I, Ledbetter S, Hayashida T
PLoS One
. 2016 May;
11(5):e0155534.
PMID: 27187580
Fibrosis is a final common pathway leading to loss of kidney function, in which the fibrogenic cytokine, transforming growth factor β (TGF-β), plays a central role. While previous studies showed...
8.
Schnaper H, Schubert K, Perlman S, Clark S, Hains D, Roach J, et al.
J Pediatr
. 2015 Jan;
166(2):218-9.e1.
PMID: 25620507
No abstract available.
9.
Schnaper H, Furth S, Yao L
Pediatr Nephrol
. 2014 Nov;
30(2):193-8.
PMID: 25370779
At a recent meeting of international experts on clinical aspects of progressive chronic kidney disease (CKD), an extensive analysis of extant clinical trials was used to develop more effective and...
10.
Liu X, Hubchak S, Browne J, Schnaper H
Cell Signal
. 2014 Jun;
26(10):2276-83.
PMID: 24905473
Transforming growth factor-β (TGF-β) signaling plays an important and complex role in renal fibrogenesis. The seemingly simple TGF-β/Smad cascade is intensively regulated at several levels, including crosstalk with other signaling...