Jeffrey B Kopp
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Explore the profile of Jeffrey B Kopp including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Oda Y, Nishi H, Hamano F, Yoshida T, Kita Y, Kopp J, et al.
bioRxiv
. 2025 Jan;
PMID: 39803581
Calcineurin inhibitors (CNIs) are indispensable immunosuppressants for transplant recipients and patients with autoimmune diseases, but chronic use causes nephrotoxicity, including kidney fibrosis. Why inhibiting calcineurin, a serine/threonine phosphatase, causes kidney...
2.
Yoshida T, Yang Z, Ashida S, Yu Z, Shrivastav S, Rojulpote K, et al.
bioRxiv
. 2025 Jan;
PMID: 39803526
Introduction: In USA, six million individuals with Sub-Saharan ancestry carry two high-risk variants, which increase the risk for kidney diseases. Whether APOL1 high-risk variants are independent risk factors for cardiovascular...
3.
Yoshida T, Latt K, Shrivastav S, Lu H, Reidy K, Charlton J, et al.
bioRxiv
. 2025 Jan;
PMID: 39803524
African-American women have a maternal mortality rate approximately three times higher than European-American women. This is partially due to hypertensive disorders of pregnancy, including preeclampsia. Fetal high-risk genotype increases preeclampsia...
4.
Yang H, Sun G, Yang X, Luan J, Jiao C, Song Q, et al.
Kidney Int Rep
. 2024 Dec;
9(12):3446-3454.
PMID: 39698370
Introduction: Kidney Disease Improving Global Outcomes guidelines indicate that glucocorticoids and immunosuppressants comprise the first therapeutic regimens after 4 to 6 months of treatment for high-risk primary membranous nephropathy (PMN)....
5.
6.
Liu W, Fermin D, Xu A, Kopp J, Xu Q
Exp Biol Med (Maywood)
. 2024 Oct;
249:10167.
PMID: 39360029
Aldehyde dehydrogenase 1, family member A2, is a retinoic acid-synthesizing enzyme encoded by in mice and in humans. This enzyme is indispensable for kidney development, but its role in kidney...
7.
Shakour R, Mithani Z, Kopp J, Shepherd J, Nogueira L, Espinel Z, et al.
Disaster Med Public Health Prep
. 2024 Sep;
18:e124.
PMID: 39291317
5wPatients with end stage kidney disease (ESKD) who receive in-center hemodialysis are disproportionately vulnerable to extreme weather events, including hurricanes and heat waves, that may disrupt access to healthcare providers,...
8.
Yin W, Rajvanshi P, Rogers H, Yoshida T, Kopp J, An X, et al.
Nat Commun
. 2024 Sep;
15(1):8114.
PMID: 39284834
Erythropoietin (EPO) plays a key role in energy metabolism, with EPO receptor (EpoR) expression in white adipose tissue (WAT) mediating its metabolic activity. Here, we show that male mice lacking...
9.
Yoshida T, Latt K, Rosenberg A, Santo B, Myakala K, Ishimoto Y, et al.
Elife
. 2024 Aug;
12.
PMID: 39207915
HIV disease remains prevalent in the USA and chronic kidney disease remains a major cause of morbidity in HIV-1-positive patients. Host double-stranded RNA (dsRNA)-activated protein kinase (PKR) is a sensor...
10.
Border S, Tomaszewski J, Yoshida T, Kopp J, Hodgin J, Clapp W, et al.
Sci Rep
. 2024 Jul;
14(1):17528.
PMID: 39080444
HistoLens is an open-source graphical user interface developed using MATLAB AppDesigner for visual and quantitative analysis of histological datasets. HistoLens enables users to interrogate sets of digitally annotated whole slide...