H Speijer
Overview
Explore the profile of H Speijer including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
192
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Recent Articles
1.
Speijer H, Savelkoul P, Bonten M, Stobberingh E, Tjhie J
J Clin Microbiol
. 1999 Oct;
37(11):3654-61.
PMID: 10523569
Colonization with Pseudomonas aeruginosa was studied by taking serial swab specimens from the oropharynges and anuses and tracheal and gastric aspirates from patients in an intensive care unit during a...
2.
Bonten M, Bergmans D, Speijer H, Stobberingh E
Am J Respir Crit Care Med
. 1999 Oct;
160(4):1212-9.
PMID: 10508809
We investigated the endemicity of Pseudomonas aeruginosa in intensive care units (ICUs) through analyses of surveillance cultures (from the rectum, stomach, oropharynx, and trachea; n = 1,089), and clinical cultures...
3.
Hack C, Wolbink G, Schalkwijk C, Speijer H, Hermens W, van den Bosch H
Immunol Today
. 1997 Mar;
18(3):111-5.
PMID: 9078682
The acute phase response is initiated in response to infection or physical trauma and is characterized by an increase in the levels of some plasma proteins. Here, Erik Hack and...
4.
Speijer H, Jans S, Reutelingsperger C, Hack C, Van der Vusse G, Hermens W
FEBS Lett
. 1997 Feb;
402(2-3):193-7.
PMID: 9037194
Phospholipase A2 (PLA2)-mediated hydrolysis of membrane phospholipids was measured by ellipsometry, and the inhibition of this process by annexin V was studied. Planar membranes, consisting of phosphatidylcholine, phosphatidylethanolamine, and phosphatidylserine...
5.
Speijer H, Giesen P, ZWAAL R, Hack C, Hermens W
Biophys J
. 1996 May;
70(5):2239-47.
PMID: 9172747
In phospholipid membranes attacked by phospholipase A(2) (PLA(2)), accumulation of degradation products influences the binding affinity as well as the catalytic activity of PLA(2). Such accumulation in its turn depends...
6.
Billy D, Speijer H, Lindhout T, Hemker H, Willems G
Biochemistry
. 1995 Oct;
34(41):13699-704.
PMID: 7577961
The kinetics of inhibition of prothrombinase during prothrombin conversion by antithrombin and antithrombin-heparin complexes was studied in a tubular flow reactor. Prothrombinase was assembled at a macroscopic phospholipid membrane, composed...
7.
Speijer H, Billy D, Willems G, Hemker H, Lindhout T
Thromb Haemost
. 1995 Apr;
73(4):648-53.
PMID: 7495073
The antithrombin-dependent inhibition of prothrombinase, assembled at a macroscopic surface, was studied under flow conditions utilizing a tubular flow reactor that consists of a phospholipid-coated glass capillary. Prothrombinase activity was...
8.
Billy D, Speijer H, Willems G, Hemker H, Lindhout T
J Biol Chem
. 1995 Jan;
270(3):1029-34.
PMID: 7836355
Thrombin production by the phospholipid-bound complex of blood clotting factors Xa and Va (prothrombinase) was studied in a tubular flow reactor. The inner wall of a glass capillary was coated...
9.
Speijer H, Groener J, van Ramshorst E, van Tol A
Atherosclerosis
. 1991 Oct;
90(2-3):159-68.
PMID: 1759986
Activities of cholesteryl ester transfer protein (CETP) and phospholipid transfer protein (PLTP) were measured in plasma of four vertebrate species: man, rabbit, pig, and rat. The activities were measured in...
10.
Rosing J, Tans G, Speijer H, ZWAAL R
Biochemistry
. 1988 Dec;
27(25):9048-55.
PMID: 3233222
The activation of prothrombin by factor Xa is strongly accelerated by negatively charged phospholipids plus calcium ions. In this paper we report that positively charged membranes can also stimulate prothrombin...