J Rosing
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Explore the profile of J Rosing including associated specialties, affiliations and a list of published articles.
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Articles
142
Citations
1912
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Recent Articles
1.
Tchaikovski S, Thomassen M, Stickeler E, Bremme K, Rosing J
Thromb Res
. 2021 Oct;
207:143-149.
PMID: 34634502
Introduction: Hormonal contraception is a well-known risk factor for venous thromboembolism (VTE). APC resistance and impaired functions of protein S and TFPI are thought to play an important role in...
2.
Alshaikh N, Rosing J, Thomassen M, Castoldi E, Simioni P, Hackeng T
J Thromb Haemost
. 2017 Feb;
15(5):950-960.
PMID: 28211163
Summary: Background Protein S plays an important role in the down-regulation of coagulation as cofactor for activated protein C (APC) and tissue factor pathway inhibitor (TFPI). Aim To develop functional...
3.
van Doorn P, Rosing J, Wielders S, Hackeng T, Castoldi E
J Thromb Haemost
. 2016 Nov;
15(1):140-149.
PMID: 27801970
Summary: Background Factor V (FV) is a carrier and a cofactor of the anticoagulant protein tissue factor pathway inhibitor-α (TFPIα), whose basic C-terminus binds to an acidic region in the...
4.
Thomassen M, Heinzmann A, Herfs L, Hartmann R, Dockal M, Scheiflinger F, et al.
J Thromb Haemost
. 2014 Oct;
13(1):92-100.
PMID: 25348176
Background: Tissue factor pathway inhibitor-α (TFPIα) inhibits factor Xa by forming a binary TFPI-FXa complex in a reaction that is stimulated by protein S. TF-FVIIa forms a quaternary complex with...
5.
Tchaikovski S, Thomassen M, Costa S, Bremme K, Rosing J
Thromb Res
. 2014 Sep;
134(5):1032-7.
PMID: 25260941
Introduction: Oral contraceptives (OC) increase the risk of venous thromboembolism that depends on the OC formulation and could at least partially be explained by impaired function of the protein C-system...
6.
Peraramelli S, Thomassen S, Heinzmann A, Rosing J, Hackeng T, Hartmann R, et al.
J Thromb Haemost
. 2014 Aug;
12(11):1826-37.
PMID: 25163770
Background: TFPI is a Kunitz-type protease inhibitor that downregulates the extrinsic coagulation pathway by inhibiting factor Xa (FXa) and FVIIa. All three Kunitz domains (KD1, KD2, and KD3) and protein...
7.
Raps M, Curvers J, Helmerhorst F, Ballieux B, Rosing J, Thomassen S, et al.
Thromb Res
. 2014 Jan;
133(4):640-4.
PMID: 24438944
Introduction: Use of combined hormonal contraceptives is associated with a three- to eight-fold increased risk of venous thrombosis compared with non-use. The thrombotic risk depends on the estrogen dose as...
8.
Omarova F, Uitte de Willige S, Ariens R, Rosing J, Bertina R, Castoldi E
J Thromb Haemost
. 2013 Jul;
11(9):1669-78.
PMID: 23848367
Background: Besides its role in blood clotting, fibrinogen exerts a poorly understood anticoagulant function by binding thrombin and modulating its activity. In particular, the γA/γ' fibrinogen isoform binds with high...
9.
Raps M, Rosendaal F, Ballieux B, Rosing J, Thomassen S, Helmerhorst F, et al.
J Thromb Haemost
. 2013 Feb;
11(5):855-61.
PMID: 23410231
Background: The use of combined oral contraceptives is associated with a 3- to 6-fold increased risk of venous thrombosis. This increased risk depends on the estrogen dose as well as...
10.
Peraramelli S, Thomassen S, Heinzmann A, Rosing J, Hackeng T, Hartmann R, et al.
J Thromb Haemost
. 2013 Jan;
11(4):704-14.
PMID: 23347185
Background: Tissue factor pathway inhibitor (TFPI) is a multi-Kunitz domain protease inhibitor that down-regulates the extrinsic coagulation pathway by inhibiting FXa and FVIIa. Objectives: To investigate the role of the...