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H Speijer

Explore the profile of H Speijer including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 192
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11.
Rosing J, Speijer H, ZWAAL R
Biochemistry . 1988 Jan; 27(1):8-11. PMID: 3162382
The conversion of prothrombin into thrombin, which is a crucial reaction in hemostatic plug formation, is greatly stimulated by phospholipids plus calcium ions. It has been proposed that phospholipid surfaces...
12.
Speijer H, ZWAAL R, Rosing J
Thromb Haemost . 1987 Jun; 57(3):349-55. PMID: 3310319
Purified snake venom prothrombin activators were used to probe the procoagulant properties of platelet membranes. Human platelets were able to stimulate prothrombin activation by the venom activators from Oxyuranus scutellatus...
13.
Speijer H, ZWAAL R, Rosing J
J Biol Chem . 1986 Oct; 261(28):13258-67. PMID: 3531198
The prothrombin activator from the venom of Oxyuranus scutellatus (Taipan snake) was purified by gel filtration on Sephadex G-200 and ion-exchange chromatography on QAE-Sephadex. The activator is a large protein...
14.
Speijer H, ZWAAL R, Rosing J
Thromb Res . 1985 May; 38(4):375-88. PMID: 3925588
In this paper we describe the effects of the activation peptides prothrombin fragment 1 and fragment 1.2 on factor Xa-catalyzed prothrombin activation. Prothrombin activation in free solution by either factor...