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H R MacDonald

Explore the profile of H R MacDonald including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 363
Citations 7386
Followers 0
Related Specialties
Allergy & Immunology
General Medicine
Science
Top 10 Co-Authors
J C Cerottini
R K Lees
A Wilson
M Nabholz
H Acha-Orbea
W HELD
R C Howe
C Bron
B Sordat
J W Lowenthal
Published In
J Immunol
Eur J Immunol
J Exp Med
Nature
Immunol Rev
Affiliations
Soon will be listed here.
Recent Articles
1.
DL4-mediated Notch signaling is required for the development of fetal αβ and γδ T cells
Ferrero I, Koch U, Claudinot S, Favre S, Radtke F, Luther S, et al.
Eur J Immunol . 2013 Jul; 43(11):2845-53. PMID: 23881845
T-cell development depends upon interactions between thymocytes and thymic epithelial cells (TECs). The engagement of delta-like 4 (DL4) on TECs by Notch1 expressed by blood-borne BM-derived precursors is essential for...
2.
"Au pair"
MacDonald H
Can Med Assoc J . 2010 Mar; 102(9):987. PMID: 20311621
No abstract available.
3.
Development and selection of Valpha l4i NKT cells
MacDonald H, Mycko M
Curr Top Microbiol Immunol . 2007 Jun; 314:195-212. PMID: 17593662
Valpha14 invariant natural killer T (Valpha14i NKT) cells are a unique lineage of mouse T cells that share properties with both NK cells and memory T cells. Valpha14i NKT cells...
4.
Endometrial cancer patients have a significant risk of harboring isolated tumor cells in histologically negative lymph nodes
Amezcua C, MacDonald H, Lum C, Yi W, Muderspach L, Roman L, et al.
Int J Gynecol Cancer . 2006 Jun; 16(3):1336-41. PMID: 16803526
In this study, we examine the prevalence of finding isolated tumor cells (ITCs) in negative lymph nodes of endometrial cancer patients using immunohistochemistry. Seventy-six endometrial cancer patients with lymph nodes...
5.
The tumor suppressor p16Ink4a regulates T lymphocyte survival
Bianchi T, Rufer N, MacDonald H, Migliaccio M
Oncogene . 2006 Feb; 25(29):4110-5. PMID: 16491120
In contrast to other cell cycle inhibitors, the tumor suppressor p16Ink4a is not detectable or expressed at very low levels in embryonic and adult mouse tissues, and therefore it has...
6.
CD8+ T cell development: CD4 to the rescue
MacDonald H, HELD W
Nat Immunol . 2001 Nov; 2(12):1091-2. PMID: 11725294
No abstract available.
7.
T cell receptor specificity is critical for the development of epidermal gammadelta T cells
Ferrero I, Wilson A, Beermann F, HELD W, MacDonald H
J Exp Med . 2001 Nov; 194(10):1473-83. PMID: 11714754
A particular feature of gammadelta T cell biology is that cells expressing T cell receptor (TCR) using specific Vgamma/Vdelta segments are localized in distinct epithelial sites, e.g., in mouse epidermis...
8.
Tissue-specific segregation of TCRgamma delta+ NKT cells according to phenotype TCR repertoire and activation status: parallels with TCR alphabeta+NKT cells
Lees R, Ferrero I, MacDonald H
Eur J Immunol . 2001 Oct; 31(10):2901-9. PMID: 11592065
Whereas the majority of NKT cells in the mouse express an alpha beta TCR (NKTalpha beta cells), a small subset of NKT cells express a gamma delta TCR (NKTgamma delta)....
9.
Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus
Wilson A, MacDonald H, Radtke F
J Exp Med . 2001 Oct; 194(7):1003-12. PMID: 11581321
We have recently reported that Notch 1, a member of the Notch multigene family, is essential for the development of murine T cells. Using a mouse model in which Notch...
10.
A critical role for the T cell receptor alpha-chain connecting peptide domain in positive selection of CD1-independent NKT cells
Capone M, Troesch M, Eberl G, Hausmann B, Palmer E, MacDonald H
Eur J Immunol . 2001 Jul; 31(6):1867-75. PMID: 11433383
Natural killer T (NKT) cells are a subset of mature alpha beta TCR(+) cells that co-express NK lineage markers. Whereas most NKT cells express a canonical Valpha14/Vbeta8.2 TCR and are...