H Acha-Orbea
Overview
Explore the profile of H Acha-Orbea including associated specialties, affiliations and a list of published articles.
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97
Citations
3147
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Recent Articles
1.
Duraes F, Thelemann C, Sarter K, Acha-Orbea H, Hugues S, Reith W
Tissue Antigens
. 2013 Jun;
82(1):1-15.
PMID: 23745569
It is well established that interactions between CD4(+) T cells and major histocompatibility complex class II (MHCII) positive antigen-presenting cells (APCs) of hematopoietic origin play key roles in both the...
2.
Mpandi M, Otten L, Lavanchy C, Acha-Orbea H, Finke D
J Virol
. 2003 Aug;
77(17):9369-77.
PMID: 12915552
Mouse mammary tumor virus (MMTV) infects the host via mucosal surfaces and exploits the host immune system for systemic spread and chronic infection. We have tested a neutralizing rat monoclonal...
3.
Ramirez J, Finke D, Esteban M, Kraehenbuhl J, Acha-Orbea H
Arch Virol
. 2003 May;
148(5):827-39.
PMID: 12721793
MVA is a candidate vector for vaccination against pathogens and tumors. Little is known about its behaviour in mucosal tissues. We have investigated the fate and biosafety of MVA, when...
4.
Finke D, Acha-Orbea H, Mattis A, Lipp M, Kraehenbuhl J
Immunity
. 2002 Oct;
17(3):363-73.
PMID: 12354388
CD4+CD3- cells are the predominant hematopoietic cells found in mouse fetal intestine. We prove their role as Peyer's patch (PP)-inducing cells by transfer into neonatal PP-deficient mice. To test the...
5.
Finke D, Acha-Orbea H
Eur J Immunol
. 2001 Sep;
31(9):2603-11.
PMID: 11536158
Our study describes tissue-specific migration of T and B cells during a localized anti-viral immune response. After mouse mammary tumor virus (MMTV) injection, B lymphocytes of the draining lymph node...
6.
Waldburger J, Suter T, Fontana A, Acha-Orbea H, Reith W
J Exp Med
. 2001 Aug;
194(4):393-406.
PMID: 11514597
MHC class II (MHCII) molecules play a pivotal role in the induction and regulation of immune responses. The transcriptional coactivator class II transactivator (CIITA) controls MHCII expression. The CIITA gene...
7.
Baribaud F, Wirth S, Maillard I, Valsesia S, Acha-Orbea H, DIGGELMANN H
J Virol
. 2001 Jul;
75(16):7453-61.
PMID: 11462017
Mouse mammary tumor virus (MMTV) is a retrovirus encoding a superantigen that is recognized in association with major histocompatibility complex class II by the variable region of the beta chain...
8.
Pairing of Vbeta6 with certain Valpha2 family members prevents T cell deletion by Mtv-7 superantigen
Aude-Garcia C, Attinger A, Housset D, MacDonald H, Acha-Orbea H, Marche P, et al.
Mol Immunol
. 2001 Jun;
37(16):1005-12.
PMID: 11395139
Superantigens (SAg) are proteins of bacterial or viral origin able to activate T cells by forming a trimolecular complex with both MHC class II molecules and the T cell receptor...
9.
Finke D, Baribaud F, DIGGELMANN H, Acha-Orbea H
J Immunol
. 2001 May;
166(10):6266-75.
PMID: 11342650
B cells can either differentiate in germinal centers or in extrafollicular compartments of secondary lymphoid organs. Here we show the migration properties of B cells after differentiation in murine peripheral...
10.
Maillard I, Launois P, Himmelrich H, Acha-Orbea H, DIGGELMANN H, Locksley R, et al.
Eur J Immunol
. 2001 Apr;
31(4):1288-96.
PMID: 11298356
Early production of IL-4 by LACK-reactive Vbeta4-Valpha8 CD4(+) T cells instructs aberrant Th2 cell development and susceptibility to Leishmania major in BALB / c mice. This was demonstrated using Vbeta4(+)-deficient...