H Phillip Koeffler
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Explore the profile of H Phillip Koeffler including associated specialties, affiliations and a list of published articles.
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416
Citations
17416
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Recent Articles
21.
Kanojia D, Kirtonia A, Srujana N, Jeevanandan S, Shyamsunder P, Sampath S, et al.
Pharmacol Res
. 2022 Sep;
185:106462.
PMID: 36167276
Liposarcoma, the most common soft tissue sarcoma, is a group of fat cell mesenchymal tumors with different histological subtypes. The dysregulation of long non-coding RNAs (lncRNAs) has been observed in...
22.
Banday A, Kaur A, Akagi T, Bhattarai D, Muraoka M, Dev D, et al.
J Clin Immunol
. 2022 Jun;
42(7):1434-1450.
PMID: 35726044
Purpose: Specific granule deficiency (SGD) is a rare inborn error of immunity resulting from loss-of-function variants in CEBPE gene (encoding for transcription factor C/EBPε). Although this genetic etiology has been...
23.
Kirtonia A, Pandey A, Ramachandran B, Mishra D, Dawson D, Sethi G, et al.
Cell Mol Life Sci
. 2022 Jun;
79(7):362.
PMID: 35699794
Pancreatic ductal adenocarcinoma (PDAC) is correlated with poor outcomes because of limited therapeutic options. Laminin-5 gamma-2 (LAMC2) plays a critical role in key biological processes. However, the detailed molecular mechanism...
24.
Baumer N, Tiemann J, Scheller A, Meyer T, Wittmann L, Gutierrez Suburu M, et al.
Oncogene
. 2022 Feb;
41(15):2210-2224.
PMID: 35220407
The small arginine-rich protein protamine condenses complete genomic DNA into the sperm head. Here, we applied its high RNA binding capacity for spontaneous electrostatic assembly of therapeutic nanoparticles decorated with...
25.
Shyamsunder P, Sridharan S, Madan V, Dakle P, Zeya C, Kanojia D, et al.
Int J Mol Sci
. 2022 Feb;
23(3).
PMID: 35163134
Multiple myeloma (MM) is a hematological disease marked by abnormal growth of B cells in bone marrow. Inherent chromosomal instability and DNA damage are major hallmarks of MM, which implicates...
26.
Xiao J, Kua L, Ding L, Sun Q, Myint K, Chia X, et al.
Mol Cancer Res
. 2022 Jan;
20(4):637-649.
PMID: 35022315
Implications: Our study provides the preclinical rationale for evaluating KDM6A and TGFβ in breast tumor samples as predictors for response to chemo and immunotherapy, informing personalized therapy based on these...
27.
Dinh H, Pan F, Wang G, Huang Q, Olingy C, Wu Z, et al.
Nat Commun
. 2021 Dec;
12(1):7335.
PMID: 34921160
The tumor microenvironment is a highly complex ecosystem of diverse cell types, which shape cancer biology and impact the responsiveness to therapy. Here, we analyze the microenvironment of esophageal squamous...
28.
Togami K, Chung S, Madan V, Booth C, Kenyon C, Cabal-Hierro L, et al.
Cancer Discov
. 2021 Oct;
12(2):522-541.
PMID: 34615655
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is an aggressive leukemia of plasmacytoid dendritic cells (pDC). BPDCN occurs at least three times more frequently in men than in women, but the...
29.
Li L, Yang Q, Jiang Y, Yang W, Jiang Y, Li X, et al.
Nat Commun
. 2021 Jul;
12(1):4362.
PMID: 34272396
Squamous cell carcinomas (SCCs) comprise one of the most common histologic types of human cancer. Transcriptional dysregulation of SCC cells is orchestrated by tumor protein p63 (TP63), a master transcription...
30.
Zheng Y, Huang G, C Silva T, Yang Q, Jiang Y, Koeffler H, et al.
Nat Commun
. 2021 Jun;
12(1):4106.
PMID: 34183671
No abstract available.